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Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH...

Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1e3d06d303874791b7d8c5107ec033d1

Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility

About this item

Full title

Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-11, Vol.11 (1), p.21827-21827, Article 21827

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Non-alcoholic fatty liver disease (NAFLD) constitutes a metabolic disorder with high worldwide prevalence and increasing incidence. The inflammatory progressive state, non-alcoholic steatohepatitis (NASH), leads to liver fibrosis and carcinogenesis. Here, we evaluated whether tyrosinase mutation underlies NASH pathophysiology. Tyrosinase point-muta...

Alternative Titles

Full title

Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1e3d06d303874791b7d8c5107ec033d1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1e3d06d303874791b7d8c5107ec033d1

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-00501-5

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