Physiological and Pathological Brain Activation in the Anesthetized Rat Produces Hemodynamic-Depende...
Physiological and Pathological Brain Activation in the Anesthetized Rat Produces Hemodynamic-Dependent Cortical Temperature Increases That Can Confound the BOLD fMRI Signal
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Switzerland: Frontiers Research Foundation
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English
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Switzerland: Frontiers Research Foundation
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Anesthetized rodent models are ubiquitous in pre-clinical neuroimaging studies. However, because the associated cerebral morphology and experimental methodology results in a profound negative brain-core temperature differential, cerebral temperature changes during functional activation are likely to be principally driven by local inflow of fresh, c...
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Physiological and Pathological Brain Activation in the Anesthetized Rat Produces Hemodynamic-Dependent Cortical Temperature Increases That Can Confound the BOLD fMRI Signal
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TN_cdi_doaj_primary_oai_doaj_org_article_1e4eb77c1eff4873a4073657d0929f5e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1e4eb77c1eff4873a4073657d0929f5e
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ISSN
1662-4548,1662-453X
E-ISSN
1662-453X
DOI
10.3389/fnins.2018.00550
