An Unusual Dimeric Inhibitor of Acetylcholinesterase: Cooperative Binding of Crystal Violet
An Unusual Dimeric Inhibitor of Acetylcholinesterase: Cooperative Binding of Crystal Violet
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Acetylcholinesterase (AChE) is an essential enzyme that terminates cholinergic transmission by a rapid hydrolysis of the neurotransmitter acetylcholine. AChE is an important target for treatment of various cholinergic deficiencies, including Alzheimer’s disease and myasthenia gravis. In a previous high throughput screening campaign, we identified t...
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An Unusual Dimeric Inhibitor of Acetylcholinesterase: Cooperative Binding of Crystal Violet
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TN_cdi_doaj_primary_oai_doaj_org_article_1e9683bc80cc43f3a31ebf401b9f79d2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1e9683bc80cc43f3a31ebf401b9f79d2
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ISSN
1420-3049,1431-5157
E-ISSN
1420-3049
DOI
10.3390/molecules22091433
