NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome p...
NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
NLRP3 is a cytosolic sensor triggered by different pathogen- and self-derived signals that plays a central role in a variety of pathological conditions, including sterile inflammation. The leucine-rich repeat domain is present in several innate immune receptors, where it is frequently responsible for sensing danger signals and regulation of activat...
Alternative Titles
Full title
NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1ef3edb735df4712b0a5732ea7fa1100
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1ef3edb735df4712b0a5732ea7fa1100
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-07573-4
