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ArticlesPeer ReviewedFull Text
NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway
Author / Creator:Hafner-Bratkovič, Iva ; Sušjan, Petra ; Lainšček, Duško ; Tapia-Abellán, Ana ; Cerović, Kosta ; Kadunc, Lucija ; Angosto-Bazarra, Diego ; Pelegrin, Pablo ; Jerala, Roman
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-12, Vol.9 (1), p.5182-18, Article 5182
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Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments
Author / Creator:Gradišar, Helena ; Božič, Sabina ; Doles, Tibor ; Vengust, Damjan ; Hafner-Bratkovič, Iva ; Mertelj, Alenka ; Webb, Ben ; Šali, Andrej ; Klavžar, Sandi ; Jerala, Roman
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2013-06, Vol.9 (6), p.362-366
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Cytokine-armed pyroptosis induces antitumor immunity against diverse types of tumors
Author / Creator:Orehek, Sara ; Ramuta, Taja Železnik ; Lainšček, Duško ; Malenšek, Špela ; Šala, Martin ; Benčina, Mojca ; Jerala, Roman ; Hafner-Bratkovič, Iva
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-12, Vol.15 (1), p.10801-22, Article 10801
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The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes
Author / Creator:Polymenidou, Magdalini ; Moos, Rita ; Scott, Mike ; Sigurdson, Christina ; Shi, Yong-zhong ; Yajima, Bill ; Hafner-Bratkovič, Iva ; Jerala, Roman ; Hornemann, Simone ; Wuthrich, Kurt ; Bellon, Anne ; Vey, Martin ; Garen, Graciela ; James, Michael N. G. ; Kav, Nat ; Aguzzi, Adriano
Publisher:United States: Public Library of Science
Journal title:PloS one, 2008-12, Vol.3 (12), p.e3872-e3872
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A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response
Author / Creator:Lainšček, Duško ; Fink, Tina ; Forstnerič, Vida ; Hafner-Bratkovič, Iva ; Orehek, Sara ; Strmšek, Žiga ; Manček-Keber, Mateja ; Pečan, Peter ; Esih, Hana ; Malenšek, Špela ; Aupič, Jana ; Dekleva, Petra ; Plaper, Tjaša ; Vidmar, Sara ; Kadunc, Lucija ; Benčina, Mojca ; Omersa, Neža ; Anderluh, Gregor ; Pojer, Florence ; Lau, Kelvin ; Hacker, David ; Correia, Bruno E. ; Peterhoff, David ; Wagner, Ralf ; Bergant, Valter ; Herrmann, Alexander ; Pichlmair, Andreas ; Jerala, Roman
Publisher:Switzerland: MDPI AG
Journal title:Vaccines (Basel), 2021-04, Vol.9 (5), p.431
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Effect of Hydrophobic Mutations in the H2-H3 Subdomain of Prion Protein on Stability and Conversion In Vitro and In Vivo
Author / Creator:Hafner-Bratkovič, Iva ; Gaedtke, Lars ; Ondracka, Andrej ; Veranič, Peter ; Vorberg, Ina ; Jerala, Roman
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-09, Vol.6 (9), p.e24238
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Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo
Author / Creator:Ljubetič, Ajasja ; Lapenta, Fabio ; Gradišar, Helena ; Drobnak, Igor ; Aupič, Jana ; Strmšek, Žiga ; Lainšček, Duško ; Hafner-Bratkovič, Iva ; Majerle, Andreja ; Krivec, Nuša ; Benčina, Mojca ; Pisanski, Tomaž ; Veličković, Tanja Ćirković ; Round, Adam ; Carazo, José María ; Melero, Roberto ; Jerala, Roman
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2017-11, Vol.35 (11), p.1094-1101
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The Role of Inflammasomes in Osteoarthritis and Secondary Joint Degeneration Diseases
Author / Creator:Roškar, Samo ; Hafner-Bratkovič, Iva
Publisher:Switzerland: MDPI AG
Journal title:Life (Basel, Switzerland), 2022-05, Vol.12 (5), p.731
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The complete genome sequence of a Crimean-Congo Hemorrhagic Fever virus isolated from an endemic region in Kosovo
Author / Creator:Duh, Darja ; Nichol, Stuart T ; Khristova, Marina L ; Saksida, Ana ; Hafner-Bratkovič, Iva ; Petrovec, Miroslav ; Dedushaj, Iusuf ; Ahmeti, Salih ; Avšič-Županc, Tatjana
Publisher:England: BioMed Central Ltd
Journal title:Virology journal, 2008-01, Vol.5 (1), p.7-7, Article 7
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The Relevance of Physico-Chemical Properties and Protein Corona for Evaluation of Nanoparticles Immunotoxicity—In Vitro Correlation Analysis on THP-1 Macrophages
Author / Creator:Pavlin, Mojca ; Lojk, Jasna ; Strojan, Klemen ; Hafner-Bratkovič, Iva ; Jerala, Roman ; Leonardi, Adrijana ; Križaj, Igor ; Drnovšek, Nataša ; Novak, Saša ; Veranič, Peter ; Bregar, Vladimir Boštjan
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-05, Vol.23 (11), p.6197
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Correction: Shikonin Suppresses NLRP3 and AIM2 Inflammasomes by Direct Inhibition of Caspase-1
Author / Creator:Zorman, Jernej ; Sušjan, Petra ; Hafner-Bratkovič, Iva
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-09, Vol.11 (9), p.e0163887-e0163887
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ArticlesPeer ReviewedFull Text
Shikonin Suppresses NLRP3 and AIM2 Inflammasomes by Direct Inhibition of Caspase-1
Author / Creator:Zorman, Jernej ; Sušjan, Petra ; Hafner-Bratkovič, Iva
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-07, Vol.11 (7), p.e0159826
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ArticlesPeer ReviewedFull Text
Differential Effect of Extracellular Acidic Environment on IL-1β Released from Human and Mouse Phagocytes
Author / Creator:Sušjan, Petra ; Benčina, Mojca ; Hafner-Bratkovič, Iva
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-09, Vol.21 (19), p.7229
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ArticlesFull Text
The pore-forming protein gasdermin D is a cellular redox sensor
Author / Creator:Devant, Pascal ; Borsic, Elvira ; Ngwa, Elsy M ; Thiagarajah, Jay R ; Hafner-Bratkovic, Iva ; Evavold, Charles L ; Kagan, Jonathan C
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-03
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ArticlesPeer ReviewedFull Text
NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity
Author / Creator:Hafner-Bratkovič, Iva ; Benčina, Mojca ; Fitzgerald, Katherine A ; Golenbock, Douglas ; Jerala, Roman
Publisher:Basel: Springer-Verlag
Journal title:Cellular and molecular life sciences : CMLS, 2012-12, Vol.69 (24), p.4215-4228
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ArticlesPeer ReviewedFull Text
Analysis of the Direct and Indirect Effects of Nanoparticle Exposure on Microglial and Neuronal Cells In Vitro
Author / Creator:Lojk, Jasna ; Babič, Lea ; Sušjan, Petra ; Bregar, Vladimir Boštjan ; Pavlin, Mojca ; Hafner-Bratkovič, Iva ; Veranič, Peter
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-10, Vol.21 (19), p.7030
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Attachment of Cancer Urothelial Cells to the Bladder Epithelium Occurs on Uroplakin-Negative Cells and Is Mediated by Desmosomal and Not by Classical Cadherins
Author / Creator:Jerman, Urška Dragin ; Višnjar, Tanja ; Bratkovič, Iva Hafner ; Resnik, Nataša ; Pavlin, Mojca ; Veranič, Peter ; Kreft, Mateja Erdani
Publisher:MDPI
Journal title:International journal of molecular sciences, 2021-05, Vol.22 (11), p.5565
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Clustering of NLRP3 induced by membrane or protein scaffolds promotes inflammasome assembly
Author / Creator:Boršić, Elvira ; Ramuta, Taja Železnik ; Orehek, Sara ; Kreft, Mateja Erdani ; Geyer, Matthias ; Jerala, Roman ; Hafner-Bratkovič, Iva
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-05, Vol.16 (1), p.4887, Article 4887
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Immune response to vaccine candidates based on different types of nanoscaffolded RBD domain of the SARS-CoV-2 spike protein
Author / Creator:Lainscek, Dusko ; Fink, Tina ; stneric, Vida ; Hafner-Bratkovic, Iva ; Orehek, Sara ; Strmsek, Ziga ; Keber, Mateja Mancek ; Pecan, Peter ; Esih, Hana ; Malensek, Spela ; Aupic, Jana ; Dekleva, Petra ; Plaper, Tjasa ; Vidmar, Sara ; Kadunc, Lucija ; Bencina, Mojca ; Pojer, Florence ; Lau, Kelvin ; Hacker, David ; Correia, Bruno ; Peterhoff, David ; Wagner, Ralf ; Jerala, Roman
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-08
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ArticlesPeer ReviewedFull Text
The NLRP3 inhibitor MCC950 inhibits IL-1β production in PBMC from 19 patients with Cryopyrin-Associated Periodic Syndrome and in 2 patients with Schnitzler’s Syndrome
Author / Creator:Corcoran, Sarah E. ; Hafner-Bratkovič, Iva ; Halai, Reena ; Domingo-Fernandez, Raquel ; O'Leary, Daire ; Banahan, Kathy ; Jerala, Roman ; Conlon, Niall ; Jung, Thomas ; O'Neill, Luke A.J. ; Cooper, Matthew A. ; Irvine, Alan D.
Publisher:London: Wellcome Trust Limited
Journal title:Wellcome open research, 2020-10, Vol.5, p.247
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NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway

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Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments

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Cytokine-armed pyroptosis induces antitumor immunity against diverse types of tumors

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The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes

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A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response

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Effect of Hydrophobic Mutations in the H2-H3 Subdomain of Prion Protein on Stability and Conversion In Vitro and In Vivo

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Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo

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The Role of Inflammasomes in Osteoarthritis and Secondary Joint Degeneration Diseases

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The complete genome sequence of a Crimean-Congo Hemorrhagic Fever virus isolated from an endemic region in Kosovo

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The Relevance of Physico-Chemical Properties and Protein Corona for Evaluation of Nanoparticles Immunotoxicity—In Vitro Correlation Analysis on THP-1 Macrophages

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Correction: Shikonin Suppresses NLRP3 and AIM2 Inflammasomes by Direct Inhibition of Caspase-1

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Shikonin Suppresses NLRP3 and AIM2 Inflammasomes by Direct Inhibition of Caspase-1

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Differential Effect of Extracellular Acidic Environment on IL-1β Released from Human and Mouse Phagocytes

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The pore-forming protein gasdermin D is a cellular redox sensor

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NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity

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Analysis of the Direct and Indirect Effects of Nanoparticle Exposure on Microglial and Neuronal Cells In Vitro

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Attachment of Cancer Urothelial Cells to the Bladder Epithelium Occurs on Uroplakin-Negative Cells and Is Mediated by Desmosomal and Not by Classical Cadherins

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Clustering of NLRP3 induced by membrane or protein scaffolds promotes inflammasome assembly

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Immune response to vaccine candidates based on different types of nanoscaffolded RBD domain of the SARS-CoV-2 spike protein

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The NLRP3 inhibitor MCC950 inhibits IL-1β production in PBMC from 19 patients with Cryopyrin-Associated Periodic Syndrome and in 2 patients with Schnitzler’s Syndrome

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