Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of...
Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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It was recently revealed that gut microbiota promote amyloid-beta (Aβ) burden in mouse models of Alzheimer’s disease (AD). However, the underlying mechanisms when using either germ-free (GF) housing conditions or treatments with antibiotics (ABX) remained unknown. In this study, we show that GF and ABX-treated 5x familial AD (5xFAD) mice developed...
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Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_1ef4ef2c7b524187aa55817e1899a3d0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1ef4ef2c7b524187aa55817e1899a3d0
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-020-00988-5
