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ArticlesPeer ReviewedFull Text
IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo
Author / Creator:Sommereyns, Caroline ; Paul, Sophie ; Staeheli, Peter ; Michiels, Thomas
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2008-03, Vol.4 (3), p.e1000017-e1000017
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Leukocyte-Derived IFN-α/β and Epithelial IFN-λ Constitute a Compartmentalized Mucosal Defense System that Restricts Enteric Virus Infections
Author / Creator:Mahlakõiv, Tanel ; Hernandez, Pedro ; Gronke, Konrad ; Diefenbach, Andreas ; Staeheli, Peter
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2015-04, Vol.11 (4), p.e1004782-e1004782
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Host microbiota constantly control maturation and function of microglia in the CNS
Author / Creator:Erny, Daniel ; Hrabě de Angelis, Anna Lena ; Jaitin, Diego ; Wieghofer, Peter ; Staszewski, Ori ; David, Eyal ; Keren-Shaul, Hadas ; Mahlakoiv, Tanel ; Jakobshagen, Kristin ; Buch, Thorsten ; Schwierzeck, Vera ; Utermöhlen, Olaf ; Chun, Eunyoung ; Garrett, Wendy S ; McCoy, Kathy D ; Diefenbach, Andreas ; Staeheli, Peter ; Stecher, Bärbel ; Amit, Ido ; Prinz, Marco
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2015-07, Vol.18 (7), p.965-977
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ArticlesPeer ReviewedFull Text
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway
Author / Creator:Holze, Cathleen ; Michaudel, Chloé ; Mackowiak, Claire ; Haas, Darya A. ; Benda, Christian ; Hubel, Philipp ; Pennemann, Friederike L. ; Schnepf, Daniel ; Wettmarshausen, Jennifer ; Braun, Marianne ; Leung, Daisy W. ; Amarasinghe, Gaya K. ; Perocchi, Fabiana ; Staeheli, Peter ; Ryffel, Bernhard ; Pichlmair, Andreas
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2018-02, Vol.19 (2), p.130-140
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IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission
Author / Creator:Klinkhammer, Jonas ; Schnepf, Daniel ; Ye, Liang ; Schwaderlapp, Marilena ; Gad, Hans Henrik ; Hartmann, Rune ; Garcin, Dominique ; Mahlakõiv, Tanel ; Staeheli, Peter
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2018-04, Vol.7
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Type I and Type III Interferons Drive Redundant Amplification Loops to Induce a Transcriptional Signature in Influenza-Infected Airway Epithelia
Author / Creator:Crotta, Stefania ; Davidson, Sophia ; Mahlakoiv, Tanel ; Desmet, Christophe J. ; Buckwalter, Matthew R. ; Albert, Matthew L. ; Staeheli, Peter ; Wack, Andreas
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2013-11, Vol.9 (11), p.e1003773-e1003773
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Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease
Author / Creator:Pillai, Padmini S. ; Molony, Ryan D. ; Martinod, Kimberly ; Dong, Huiping ; Pang, Iris K. ; Tal, Michal C. ; Solis, Angel G. ; Bielecki, Piotr ; Mohanty, Subhasis ; Trentalange, Mark ; Homer, Robert J. ; Flavell, Richard A. ; Wagner, Denisa D. ; Montgomery, Ruth R. ; Shaw, Albert C. ; Staeheli, Peter ; Iwasaki, Akiko
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-04, Vol.352 (6284), p.463-466
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IFN-λ determines the intestinal epithelial antiviral host defense
Author / Creator:Pott, Johanna ; Mahlakõiv, Tanel ; Mordstein, Markus ; Duerr, Claudia U. ; Michiels, Thomas ; Stockinger, Silvia ; Staeheli, Peter ; Hornef, Mathias W. ; Hiscott, John
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (19), p.7944-7949
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Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma
Author / Creator:Beug, Shawn T. ; Beauregard, Caroline E. ; Healy, Cristin ; Sanda, Tarun ; St-Jean, Martine ; Chabot, Janelle ; Walker, Danielle E. ; Mohan, Aditya ; Earl, Nathalie ; Lun, Xueqing ; Senger, Donna L. ; Robbins, Stephen M. ; Staeheli, Peter ; Forsyth, Peter A. ; Alain, Tommy ; LaCasse, Eric C. ; Korneluk, Robert G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-02, Vol.8 (1), p.1-15, Article 14278
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ArticlesPeer ReviewedFull Text
mRNA 3’UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus
Author / Creator:Bergant, Valter ; Schnepf, Daniel ; de Andrade Krätzig, Niklas ; Hubel, Philipp ; Urban, Christian ; Engleitner, Thomas ; Dijkman, Ronald ; Ryffel, Bernhard ; Steiger, Katja ; Knolle, Percy A. ; Kochs, Georg ; Rad, Roland ; Staeheli, Peter ; Pichlmair, Andreas
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-08, Vol.14 (1), p.4906-4906, Article 4906
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ArticlesPeer ReviewedFull Text
Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease
Author / Creator:Mezö, Charlotte ; Dokalis, Nikolaos ; Mossad, Omar ; Staszewski, Ori ; Neuber, Jana ; Yilmaz, Bahtiyar ; Schnepf, Daniel ; de Agüero, Mercedes Gomez ; Ganal-Vonarburg, Stephanie C. ; Macpherson, Andrew J. ; Meyer-Luehmann, Melanie ; Staeheli, Peter ; Blank, Thomas ; Prinz, Marco ; Erny, Daniel
Publisher:London: BioMed Central Ltd
Journal title:Acta neuropathologica communications, 2020-07, Vol.8 (1), p.1-119, Article 119
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ArticlesPeer ReviewedFull Text
Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses
Author / Creator:Mordstein, Markus ; Kochs, Georg ; Dumoutier, Laure ; Renauld, Jean-Christophe ; Paludan, Søren R. ; Klucher, Kevin ; Staeheli, Peter
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2008-09, Vol.4 (9), p.e1000151-e1000151
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ArticlesPeer ReviewedFull Text
Neurons Produce Type I Interferon during Viral Encephalitis
Author / Creator:Delhaye, Sophie ; Paul, Sophie ; Blakqori, Gjon ; Minet, Muriel ; Weber, Friedemann ; Staeheli, Peter ; Michiels, Thomas
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (20), p.7835-7840
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ArticlesPeer ReviewedFull Text
Human but Not Mouse Hepatocytes Respond to Interferon-Lambda In Vivo
Author / Creator:Hermant, Pascale ; Demarez, Céline ; Mahlakõiv, Tanel ; Staeheli, Peter ; Meuleman, Philip ; Michiels, Thomas
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-01, Vol.9 (1), p.e87906-e87906
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ArticlesPeer ReviewedFull Text
Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance
Author / Creator:Swamy, Mahima ; Abeler-Dörner, Lucie ; Chettle, James ; Mahlakõiv, Tanel ; Goubau, Delphine ; Chakravarty, Probir ; Ramsay, George ; Reis e Sousa, Caetano ; Staeheli, Peter ; Blacklaws, Barbara A. ; Heeney, Jonathan L. ; Hayday, Adrian C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-05, Vol.6 (1), p.7090, Article 7090
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The alternative cap-binding complex is required for antiviral defense in vivo
Author / Creator:Gebhardt, Anna ; Bergant, Valter ; Schnepf, Daniel ; Moser, Markus ; Meiler, Arno ; Togbe, Dieudonnée ; Mackowiak, Claire ; Reinert, Line S. ; Paludan, Søren R. ; Ryffel, Bernhard ; Stukalov, Alexey ; Staeheli, Peter ; Pichlmair, Andreas
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2019-12, Vol.15 (12), p.e1008155-e1008155
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Activation of Type III Interferon Genes by Pathogenic Bacteria in Infected Epithelial Cells and Mouse Placenta
Author / Creator:Bierne, Hélène ; Travier, Laetitia ; Mahlakõiv, Tanel ; Tailleux, Ludovic ; Subtil, Agathe ; Lebreton, Alice ; Paliwal, Anupam ; Gicquel, Brigitte ; Staeheli, Peter ; Lecuit, Marc ; Cossart, Pascale
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-06, Vol.7 (6), p.e39080-e39080
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ArticlesPeer ReviewedFull Text
Rotavirus susceptibility of antibiotic-treated mice ascribed to diminished expression of interleukin-22
Author / Creator:Schnepf, Daniel ; Hernandez, Pedro ; Mahlakõiv, Tanel ; Crotta, Stefania ; Sullender, Meagan E. ; Peterson, Stefan T. ; Ohnemus, Annette ; Michiels, Camille ; Gentle, Ian ; Dumoutier, Laure ; Reis, Celso A. ; Diefenbach, Andreas ; Wack, Andreas ; Baldridge, Megan T. ; Staeheli, Peter
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-08, Vol.16 (8), p.e0247738
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Antagonism of interferon signaling by fibroblast growth factors promotes viral replication
Author / Creator:Maddaluno, Luigi ; Urwyler, Corinne ; Rauschendorfer, Theresa ; Meyer, Michael ; Stefanova, Debora ; Spörri, Roman ; Wietecha, Mateusz ; Ferrarese, Luca ; Stoycheva, Diana ; Bender, Daniela ; Li, Nick ; Strittmatter, Gerhard ; Nasirujjaman, Khondokar ; Beer, Hans‐Dietmar ; Staeheli, Peter ; Hildt, Eberhard ; Oxenius, Annette ; Werner, Sabine
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2020-09, Vol.12 (9), p.e11793-n/a
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S. mansoni Bolsters Anti-Viral Immunity in the Murine Respiratory Tract
Author / Creator:Scheer, Sebastian ; Krempl, Christine ; Kallfass, Carsten ; Frey, Stefanie ; Jakob, Thilo ; Mouahid, Gabriel ; Moné, Hélène ; Schmitt-Gräff, Annette ; Staeheli, Peter ; Lamers, Marinus C.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-11, Vol.9 (11), p.e112469-e112469
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Showing 1 to 20 of 85 results

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IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

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Leukocyte-Derived IFN-α/β and Epithelial IFN-λ Constitute a Compartmentalized Mucosal Defense System that Restricts Enteric Virus Infections

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Host microbiota constantly control maturation and function of microglia in the CNS

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Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway

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IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission

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Type I and Type III Interferons Drive Redundant Amplification Loops to Induce a Transcriptional Signature in Influenza-Infected Airway Epithelia

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Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease

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IFN-λ determines the intestinal epithelial antiviral host defense

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Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma

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mRNA 3’UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus

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Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease

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Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses

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Neurons Produce Type I Interferon during Viral Encephalitis

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Human but Not Mouse Hepatocytes Respond to Interferon-Lambda In Vivo

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Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance

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The alternative cap-binding complex is required for antiviral defense in vivo

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Activation of Type III Interferon Genes by Pathogenic Bacteria in Infected Epithelial Cells and Mouse Placenta

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Rotavirus susceptibility of antibiotic-treated mice ascribed to diminished expression of interleukin-22

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Antagonism of interferon signaling by fibroblast growth factors promotes viral replication

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S. mansoni Bolsters Anti-Viral Immunity in the Murine Respiratory Tract

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