Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk predi...
Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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A promise of genomics in precision medicine is to provide individualized genetic risk predictions. Polygenic risk scores (PRS), computed by aggregating effects from many genomic variants, have been developed as a useful tool in complex disease research. However, the application of PRS as a tool for predicting an individual’s disease susceptibility...
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Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction
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TN_cdi_doaj_primary_oai_doaj_org_article_1f27829d10184dee8d91f723afe0978e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1f27829d10184dee8d91f723afe0978e
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25014-7
