Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation...
Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Although mouse models exist for many immune-based diseases, the clinical translation remains challenging. Most basic and translational studies utilize only a single inbred mouse strain. However, basal and diseased immune states in humans show vast inter-individual variability. Here, focusing on macrophage responses to lipopolysaccharide (LPS), we u...
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Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival
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TN_cdi_doaj_primary_oai_doaj_org_article_1fc27041918b48b8a2944c3034860cf1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1fc27041918b48b8a2944c3034860cf1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms16041
