CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurod...
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline
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Author / Creator
Suárez‐Calvet, Marc , Capell, Anja , Araque Caballero, Miguel Ángel , Morenas‐Rodríguez, Estrella , Fellerer, Katrin , Franzmeier, Nicolai , Kleinberger, Gernot , Eren, Erden , Deming, Yuetiva , Piccio, Laura , Karch, Celeste M , Cruchaga, Carlos , Paumier, Katrina , Bateman, Randall J , Fagan, Anne M , Morris, John C , Levin, Johannes , Danek, Adrian , Jucker, Mathias , Masters, Colin L , Rossor, Martin N , Ringman, John M , Shaw, Leslie M , Trojanowski, John Q , Weiner, Michael , Ewers, Michael , Haass, Christian , Alzheimer's Disease Neuroimaging Initiative and Dominantly Inherited Alzheimer Network
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Progranulin (PGRN) is predominantly expressed by microglia in the brain, and genetic and experimental evidence suggests a critical role in Alzheimer's disease (AD). We asked whether PGRN expression is changed in a disease severity‐specific manner in AD. We measured PGRN in cerebrospinal fluid (CSF) in two of the best‐characterized AD patient cohort...
Alternative Titles
Full title
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline
Authors, Artists and Contributors
Author / Creator
Capell, Anja
Araque Caballero, Miguel Ángel
Morenas‐Rodríguez, Estrella
Fellerer, Katrin
Franzmeier, Nicolai
Kleinberger, Gernot
Eren, Erden
Deming, Yuetiva
Piccio, Laura
Karch, Celeste M
Cruchaga, Carlos
Paumier, Katrina
Bateman, Randall J
Fagan, Anne M
Morris, John C
Levin, Johannes
Danek, Adrian
Jucker, Mathias
Masters, Colin L
Rossor, Martin N
Ringman, John M
Shaw, Leslie M
Trojanowski, John Q
Weiner, Michael
Ewers, Michael
Haass, Christian
Alzheimer's Disease Neuroimaging Initiative
Dominantly Inherited Alzheimer Network
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1fe5940f23884dd28924de1e2c522e1d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1fe5940f23884dd28924de1e2c522e1d
Other Identifiers
ISSN
1757-4676,1757-4684
E-ISSN
1757-4684
DOI
10.15252/emmm.201809712
