The lipophilic cyclic peptide cyclosporin A induces aggregation of gel-forming mucins
The lipophilic cyclic peptide cyclosporin A induces aggregation of gel-forming mucins
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Cyclic peptides are good candidates for orally delivered therapeutics, however, issues remain in their development due to low intestinal permeability. Although some of the biological factors have been reported that regulate intestinal permeation of cyclic peptides, the influence of the mucus barrier, a major hurdle to epithelial drug delivery, on c...
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Full title
The lipophilic cyclic peptide cyclosporin A induces aggregation of gel-forming mucins
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TN_cdi_doaj_primary_oai_doaj_org_article_2063075387d247ef9bb4fa2bd6ca903a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2063075387d247ef9bb4fa2bd6ca903a
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-10125-y
