Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution
Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Reprogramming of the NRPS/PKS assembly line is an attractive method for the production of new bioactive molecules. However, it is usually hampered by the loss of intimate domain/module interactions required for the precise control of chain transfer and elongation reactions. In this study, we first establish heterologous expression systems of the un...
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Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution
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TN_cdi_doaj_primary_oai_doaj_org_article_209bc4d1b5344a32b292f405caa6ac8b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_209bc4d1b5344a32b292f405caa6ac8b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05877-z
