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ArticlesPeer ReviewedFull Text
Terpene synthases are widely distributed in bacteria
Author / Creator:Yamada, Yuuki ; Kuzuyama, Tomohisa ; Komatsu, Mamoru ; Shin-ya, Kazuo ; Omura, Satoshi ; Cane, David E. ; Ikeda, Haruo
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-01, Vol.112 (3), p.857-862
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Gastric myotomy length affects severity but not rate of post-procedure reflux: 3-year follow-up of a prospective randomized controlled trial of double-scope per-oral endoscopic myotomy (POEM) for esop...
Author / Creator:Grimes, Kevin L. ; Bechara, Robert ; Shimamura, Yuto ; Ikeda, Haruo ; Inoue, Haruhiro
Publisher:New York: Springer US
Journal title:Surgical endoscopy, 2020-07, Vol.34 (7), p.2963-2968
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Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters
Author / Creator:Ikeda, Haruo ; Shin-ya, Kazuo ; Omura, Satoshi
Publisher:Germany: Springer-Verlag
Journal title:Journal of industrial microbiology & biotechnology, 2014-02, Vol.41 (2), p.233-250
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Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo
Author / Creator:Ozaki, Taro ; Yamashita, Kona ; Goto, Yuki ; Shimomura, Morito ; Hayashi, Shohei ; Asamizu, Shumpei ; Sugai, Yoshinori ; Ikeda, Haruo ; Suga, Hiroaki ; Onaka, Hiroyasu
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-02, Vol.8 (1), p.14207-14207, Article 14207
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ArticlesPeer ReviewedFull Text
Peroral endoscopic myotomy: an evolving treatment for achalasia
Author / Creator:Bechara, Robert ; Ikeda, Haruo ; Inoue, Haruhiro
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Gastroenterology & hepatology, 2015-07, Vol.12 (7), p.410-426
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ArticlesPeer ReviewedFull Text
Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism
Author / Creator:Komatsu, Mamoru ; Uchiyama, Takuma ; Ōmura, Satoshi ; Cane, David E ; Ikeda, Haruo
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (6), p.2646-2651
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In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives
Author / Creator:Kudo, Kei ; Hashimoto, Takuya ; Hashimoto, Junko ; Kozone, Ikuko ; Kagaya, Noritaka ; Ueoka, Reiko ; Nishimura, Takehiro ; Komatsu, Mamoru ; Suenaga, Hikaru ; Ikeda, Haruo ; Shin-ya, Kazuo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-08, Vol.11 (1), p.4022-4022, Article 4022
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Discovery of prescopranone, a key intermediate in scopranone biosynthesis
Author / Creator:Demachi, Ayumu ; Ohte, Satoshi ; Uchida, Ryuji ; Shin-ya, Kazuo ; Ohshiro, Taichi ; Tomoda, Hiroshi ; Ikeda, Haruo
Publisher:London: Nature Publishing Group UK
Journal title:Journal of antibiotics, 2022-06, Vol.75 (6), p.305-311
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Actinobacterial chalkophores: the biosynthesis of hazimycins
Author / Creator:Matsuda, Kenichi ; Maruyama, Hiroto ; Imachi, Kumiko ; Ikeda, Haruo ; Wakimoto, Toshiyuki
Publisher:Tokyo: Springer Japan
Journal title:Journal of antibiotics, 2024-04, Vol.77 (4), p.228-237
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Novel macrolactam compound produced by the heterologous expression of a large cryptic biosynthetic gene cluster of Streptomyces rochei IFO12908
Author / Creator:Hashimoto, Takuya ; Kozone, Ikuko ; Hashimoto, Junko ; Ueoka, Reiko ; Kagaya, Noritaka ; Fujie, Manabu ; Sato, Noriyuki ; Ikeda, Haruo ; Shin-ya, Kazuo
Publisher:London: Nature Publishing Group UK
Journal title:Journal of antibiotics, 2020-03, Vol.73 (3), p.171-174
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ArticlesPeer ReviewedFull Text
Identification, cloning and heterologous expression of biosynthetic gene cluster for desertomycin
Author / Creator:Hashimoto, Takuya ; Kozone, Ikuko ; Hashimoto, Junko ; Suenaga, Hikaru ; Fujie, Manabu ; Satoh, Noriyuki ; Ikeda, Haruo ; Shin-ya, Kazuo
Publisher:London: Nature Publishing Group UK
Journal title:Journal of antibiotics, 2020-09, Vol.73 (9), p.650-654
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Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution
Author / Creator:Awakawa, Takayoshi ; Fujioka, Takuma ; Zhang, Lihan ; Hoshino, Shotaro ; Hu, Zhijuan ; Hashimoto, Junko ; Kozone, Ikuko ; Ikeda, Haruo ; Shin-Ya, Kazuo ; Liu, Wen ; Abe, Ikuro
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-08, Vol.9 (1), p.3534-10, Article 3534
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ArticlesPeer ReviewedFull Text
Utility of a new automated diagnostic program in high-resolution esophageal manometry
Author / Creator:Kuribayashi, Shiko ; Akiyama, Junichi ; Ikeda, Haruo ; Nagai, Kazue ; Hosaka, Hiroko ; Hamada, Mariko ; Onimaru, Manabu ; Kawami, Noriyuki ; Hayashi, Kunihiko ; Iwakiri, Katsuhiko ; Inoue, Haruhiro ; Kusano, Motoyasu ; Uraoka, Toshio
Publisher:Singapore: Springer Singapore
Journal title:Journal of gastroenterology, 2021-07, Vol.56 (7), p.633-639
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ArticlesPeer ReviewedFull Text
Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol
Author / Creator:Komatsu, Mamoru ; Tsuda, Muneya ; Ōmura, Satoshi ; Oikawa, Hideaki ; Ikeda, Haruo
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (21), p.7422-7427
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ArticlesPeer ReviewedFull Text
Double-scope per oral endoscopic myotomy (POEM): a prospective randomized controlled trial
Author / Creator:Grimes, Kevin L. ; Inoue, Haruhiro ; Onimaru, Manabu ; Ikeda, Haruo ; Tansawet, Amarit ; Bechara, Robert ; Tanaka, Shinwa
Publisher:New York: Springer US
Journal title:Surgical endoscopy, 2016-04, Vol.30 (4), p.1344-1351
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ArticlesPeer ReviewedFull Text
Chemical diversity of labdane-type bicyclic diterpene biosynthesis in Actinomycetales microorganisms
Author / Creator:Yamada, Yuuki ; Komatsu, Mamoru ; Ikeda, Haruo
Publisher:London: Nature Publishing Group UK
Journal title:Journal of antibiotics, 2016-07, Vol.69 (7), p.515-523
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Characterization of bafilomycin biosynthesis in Kitasatospora setae KM-6054 and comparative analysis of gene clusters in Actinomycetales microorganisms
Author / Creator:Nara, Ayako ; Hashimoto, Takuya ; Komatsu, Mamoru ; Nishiyama, Makoto ; Kuzuyama, Tomohisa ; Ikeda, Haruo
Publisher:London: Nature Publishing Group UK
Journal title:Journal of antibiotics, 2017-05, Vol.70 (5), p.616-624
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Hemiacetal-less rapamycin derivatives designed and produced by genetic engineering of a type I polyketide synthase
Author / Creator:Kudo, Kei ; Nishimura, Takehiro ; Kozone, Ikuko ; Hashimoto, Junko ; Kagaya, Noritaka ; Suenaga, Hikaru ; Ikeda, Haruo ; Shin-ya, Kazuo
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-05, Vol.11 (1), p.9944-9944, Article 9944
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Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis
Author / Creator:Kitani, Shigeru ; Miyamoto, Kiyoko T ; Takamatsu, Satoshi ; Herawati, Elisa ; Iguchi, Hiroyuki ; Nishitomi, Kouhei ; Uchida, Miho ; Nagamitsu, Tohru ; Omura, Satoshi ; Ikeda, Haruo ; Nihira, Takuya
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (39), p.16410-16415
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Characterization of the biosynthetic gene cluster for cryptic phthoxazolin A in Streptomyces avermitilis
Author / Creator:Suroto, Dian Anggraini ; Kitani, Shigeru ; Arai, Masayoshi ; Ikeda, Haruo ; Nihira, Takuya
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-01, Vol.13 (1), p.e0190973-e0190973
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Showing 1 to 20 of 87 results

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Terpene synthases are widely distributed in bacteria

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Gastric myotomy length affects severity but not rate of post-procedure reflux: 3-year follow-up of a prospective randomized controlled trial of double-scope per-oral endoscopic myotomy (POEM) for esop...

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Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters

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Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo

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Peroral endoscopic myotomy: an evolving treatment for achalasia

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Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

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In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives

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Discovery of prescopranone, a key intermediate in scopranone biosynthesis

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Actinobacterial chalkophores: the biosynthesis of hazimycins

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Novel macrolactam compound produced by the heterologous expression of a large cryptic biosynthetic gene cluster of Streptomyces rochei IFO12908

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Identification, cloning and heterologous expression of biosynthetic gene cluster for desertomycin

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Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution

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Utility of a new automated diagnostic program in high-resolution esophageal manometry

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Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol

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Double-scope per oral endoscopic myotomy (POEM): a prospective randomized controlled trial

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Chemical diversity of labdane-type bicyclic diterpene biosynthesis in Actinomycetales microorganisms

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Characterization of bafilomycin biosynthesis in Kitasatospora setae KM-6054 and comparative analysis of gene clusters in Actinomycetales microorganisms

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Hemiacetal-less rapamycin derivatives designed and produced by genetic engineering of a type I polyketide synthase

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Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis

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Characterization of the biosynthetic gene cluster for cryptic phthoxazolin A in Streptomyces avermitilis

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