Interaction Characterization of a Tyrosine Kinase Inhibitor Erlotinib with a Model Transport Protein...
Interaction Characterization of a Tyrosine Kinase Inhibitor Erlotinib with a Model Transport Protein in the Presence of Quercetin: A Drug-Protein and Drug-Drug Interaction Investigation Using Multi-Spectroscopic and Computational Approaches
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Switzerland: MDPI AG
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English
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Publisher
Switzerland: MDPI AG
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The interaction between erlotinib (ERL) and bovine serum albumin (BSA) was studied in the presence of quercetin (QUR), a flavonoid with antioxidant properties. Ligands bind to the transport protein BSA resulting in competition between different ligands and displacing a bound ligand, resulting in higher plasma concentrations. Therefore, various spec...
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Full title
Interaction Characterization of a Tyrosine Kinase Inhibitor Erlotinib with a Model Transport Protein in the Presence of Quercetin: A Drug-Protein and Drug-Drug Interaction Investigation Using Multi-Spectroscopic and Computational Approaches
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TN_cdi_doaj_primary_oai_doaj_org_article_2123c142dbfa4aa597cd72c1c78ed0c2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2123c142dbfa4aa597cd72c1c78ed0c2
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules27041265
