Structural basis for nuclear import selectivity of pioneer transcription factor SOX2
Structural basis for nuclear import selectivity of pioneer transcription factor SOX2
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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SOX (SRY-related HMG-box) transcription factors perform critical functions in development and cell differentiation. These roles depend on precise nuclear trafficking, with mutations in the nuclear targeting regions causing developmental diseases and a range of cancers. SOX protein nuclear localization is proposed to be mediated by two nuclear local...
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Structural basis for nuclear import selectivity of pioneer transcription factor SOX2
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TN_cdi_doaj_primary_oai_doaj_org_article_213cab1ef68b41cbaac148926dd0be5d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_213cab1ef68b41cbaac148926dd0be5d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20194-0
