Footprints of antigen processing boost MHC class II natural ligand predictions
Footprints of antigen processing boost MHC class II natural ligand predictions
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Major histocompatibility complex class II (MHC-II) molecules present peptide fragments to T cells for immune recognition. Current predictors for peptide to MHC-II binding are trained on binding affinity data, generated in vitro and therefore lacking information about antigen processing.
We generate prediction models of peptide to MHC-II binding...
Alternative Titles
Full title
Footprints of antigen processing boost MHC class II natural ligand predictions
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_215cc6667adf4b839c3cd25b83214bef
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_215cc6667adf4b839c3cd25b83214bef
Other Identifiers
ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-018-0594-6
