Clusterin protects neurons against intracellular proteotoxicity
Clusterin protects neurons against intracellular proteotoxicity
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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It is now widely accepted in the field that the normally secreted chaperone clusterin is redirected to the cytosol during endoplasmic reticulum (ER) stress, although the physiological function(s) of this physical relocation remain unknown. We have examined in this study whether or not increased expression of clusterin is able to protect neuronal ce...
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Clusterin protects neurons against intracellular proteotoxicity
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TN_cdi_doaj_primary_oai_doaj_org_article_21bc7900713e4ebdb657794a389341be
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21bc7900713e4ebdb657794a389341be
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-017-0481-1