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Clusterin protects neurons against intracellular proteotoxicity

Clusterin protects neurons against intracellular proteotoxicity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21bc7900713e4ebdb657794a389341be

Clusterin protects neurons against intracellular proteotoxicity

About this item

Full title

Clusterin protects neurons against intracellular proteotoxicity

Publisher

England: BioMed Central Ltd

Journal title

Acta neuropathologica communications, 2017-11, Vol.5 (1), p.81-16, Article 81

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

It is now widely accepted in the field that the normally secreted chaperone clusterin is redirected to the cytosol during endoplasmic reticulum (ER) stress, although the physiological function(s) of this physical relocation remain unknown. We have examined in this study whether or not increased expression of clusterin is able to protect neuronal ce...

Alternative Titles

Full title

Clusterin protects neurons against intracellular proteotoxicity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_21bc7900713e4ebdb657794a389341be

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21bc7900713e4ebdb657794a389341be

Other Identifiers

ISSN

2051-5960

E-ISSN

2051-5960

DOI

10.1186/s40478-017-0481-1

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