Recent natural selection conferred protection against schizophrenia by non-antagonistic pleiotropy
Recent natural selection conferred protection against schizophrenia by non-antagonistic pleiotropy
About this item
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Author / Creator
González-Peñas, Javier , de Hoyos, Lucía , Díaz-Caneja, Covadonga M. , Andreu-Bernabeu, Álvaro , Stella, Carol , Gurriarán, Xaquín , Fañanás, Lourdes , Bobes, Julio , González-Pinto, Ana , Crespo-Facorro, Benedicto , Martorell, Lourdes , Vilella, Elisabet , Muntané, Gerard , Molto, María Dolores , Gonzalez-Piqueras, Jose Carlos , Parellada, Mara , Arango, Celso and Costas, Javier
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Schizophrenia is a debilitating psychiatric disorder associated with a reduced fertility and decreased life expectancy, yet common predisposing variation substantially contributes to the onset of the disorder, which poses an evolutionary paradox. Previous research has suggested balanced selection, a mechanism by which schizophrenia risk alleles cou...
Alternative Titles
Full title
Recent natural selection conferred protection against schizophrenia by non-antagonistic pleiotropy
Authors, Artists and Contributors
Author / Creator
de Hoyos, Lucía
Díaz-Caneja, Covadonga M.
Andreu-Bernabeu, Álvaro
Stella, Carol
Gurriarán, Xaquín
Fañanás, Lourdes
Bobes, Julio
González-Pinto, Ana
Crespo-Facorro, Benedicto
Martorell, Lourdes
Vilella, Elisabet
Muntané, Gerard
Molto, María Dolores
Gonzalez-Piqueras, Jose Carlos
Parellada, Mara
Arango, Celso
Costas, Javier
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_21d0889ee7df42efac93094fbfb094f9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21d0889ee7df42efac93094fbfb094f9
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-42578-0