IFN-β production induced by PRRSV is affected by GP3 quantity control and CLND4 interaction
IFN-β production induced by PRRSV is affected by GP3 quantity control and CLND4 interaction
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Author / Creator
Li, Dexin , Cui, Xinyu , Li, Yingchao , Zhang, Qin , Gao, Hongyan , Li, Youbo , Hou, Yanmeng , Yuan, Hongjie and Xiao, Yihong
Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most harmful pathogens in the swine industry. Our previous studies demonstrated that the small extracellular domain (ECL2) of CLDN4 effectively blocks PRRSV infection. In this study, we explored the in vivo administration of swine ECL2 (sECL2) and found that it blocked HP-PRR...
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Full title
IFN-β production induced by PRRSV is affected by GP3 quantity control and CLND4 interaction
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TN_cdi_doaj_primary_oai_doaj_org_article_21e00bed7b704c90a253ba6fd1d8f5da
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21e00bed7b704c90a253ba6fd1d8f5da
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ISSN
1297-9716,0928-4249
E-ISSN
1297-9716
DOI
10.1186/s13567-025-01455-6