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IFN-β production induced by PRRSV is affected by GP3 quantity control and CLND4 interaction

IFN-β production induced by PRRSV is affected by GP3 quantity control and CLND4 interaction

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21e00bed7b704c90a253ba6fd1d8f5da

IFN-β production induced by PRRSV is affected by GP3 quantity control and CLND4 interaction

About this item

Full title

IFN-β production induced by PRRSV is affected by GP3 quantity control and CLND4 interaction

Publisher

England: BioMed Central

Journal title

Veterinary research (Paris), 2025-01, Vol.56 (1), p.21-12, Article 21

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most harmful pathogens in the swine industry. Our previous studies demonstrated that the small extracellular domain (ECL2) of CLDN4 effectively blocks PRRSV infection. In this study, we explored the in vivo administration of swine ECL2 (sECL2) and found that it blocked HP-PRR...

Alternative Titles

Full title

IFN-β production induced by PRRSV is affected by GP3 quantity control and CLND4 interaction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_21e00bed7b704c90a253ba6fd1d8f5da

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21e00bed7b704c90a253ba6fd1d8f5da

Other Identifiers

ISSN

1297-9716,0928-4249

E-ISSN

1297-9716

DOI

10.1186/s13567-025-01455-6

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