PDZD-8 and TEX-2 regulate endosomal PI(4,5)P2 homeostasis via lipid transport to promote embryogenes...
PDZD-8 and TEX-2 regulate endosomal PI(4,5)P2 homeostasis via lipid transport to promote embryogenesis in C. elegans
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Different types of cellular membranes have unique lipid compositions that are important for their functional identity. PI(4,5)P
2
is enriched in the plasma membrane where it contributes to local activation of key cellular events, including actomyosin contraction and cytokinesis. However, how cells prevent PI(4,5)P
2
from accumulating in...
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Full title
PDZD-8 and TEX-2 regulate endosomal PI(4,5)P2 homeostasis via lipid transport to promote embryogenesis in C. elegans
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TN_cdi_doaj_primary_oai_doaj_org_article_222d609dadd7476c866af15d5aadaf60
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_222d609dadd7476c866af15d5aadaf60
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-26177-z
