AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma
AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma
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Author / Creator
Zhu, Qing , Ma, Yarui , Liang, Junbo , Wei, Zhewen , Li, Mo , Zhang, Ying , Liu, Mei , He, Huan , Qu, Chunfeng , Cai, Jianqiang , Wang, Xiaobing , Zeng, Yixin and Jiao, Yuchen
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Aflatoxin exposure is a crucial factor in promoting the development of primary hepatocellular carcinoma (HCC) in individuals infected with the hepatitis virus. However, the molecular pathways leading to its bioactivation and subsequent toxicity in hepatocytes have not been well-defined. Here, we carried out a genome-wide CRISPR-Cas9 genetic screen...
Alternative Titles
Full title
AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_223970bd249a44a1a154aad32ccd7519
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_223970bd249a44a1a154aad32ccd7519
Other Identifiers
ISSN
2059-3635,2095-9907
E-ISSN
2059-3635
DOI
10.1038/s41392-021-00713-1
