Development and Characterization of Eudragit ® EPO-Based Solid Dispersion of Rosuvastatin Calcium to...
Development and Characterization of Eudragit ® EPO-Based Solid Dispersion of Rosuvastatin Calcium to Foresee the Impact on Solubility, Dissolution and Antihyperlipidemic Activity
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Poor solubility is the major challenge involved in the formulation development of new chemical entities (NCEs), as more than 40% of NCEs are practically insoluble in water. Solid dispersion (SD) is a promising technology for improving dissolution and, thereby, the bioavailability of poorly soluble drugs. This study investigates the influence of a p...
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Development and Characterization of Eudragit ® EPO-Based Solid Dispersion of Rosuvastatin Calcium to Foresee the Impact on Solubility, Dissolution and Antihyperlipidemic Activity
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TN_cdi_doaj_primary_oai_doaj_org_article_22734906a1c44e85aef931e8d7deacb1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22734906a1c44e85aef931e8d7deacb1
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1424-8247
E-ISSN
1424-8247
DOI
10.3390/ph15040492