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Investigation of the effect of solubility increase at the main absorption site on bioavailability of BCS class II drug (risperidone) using liquisolid technique
Author / Creator:Khames, Ahmed
Publisher:Philadelphia: Taylor & Francis Ltd
Journal title:Drug delivery, 2017-01, Vol.24 (1), p.328-338
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Formulation and Characterization of Eplerenone Nanoemulsion Liquisolids, An Oral Delivery System with Higher Release Rate and Improved Bioavailability
Author / Creator:Khames, Ahmed
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2019-01, Vol.11 (1), p.40
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Computational Identification of Druggable Bioactive Compounds from Catharanthus roseus and Avicennia marina against Colorectal Cancer by Targeting Thymidylate Synthase
Author / Creator:Islam, Md Rashedul ; Awal, Md Abdul ; Khames, Ahmed ; Abourehab, Mohammad A S ; Samad, Abdus ; Hassan, Walid M I ; Alam, Rahat ; Osman, Osman I ; Nur, Suza Mohammad ; Molla, Mohammad Habibur Rahman ; Abdulrahman, Abdulrasheed O ; Rajia, Sultana ; Ahammad, Foysal ; Hasan, Md Nazmul ; Qadri, Ishtiaq ; Kim, Bonglee
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-03, Vol.27 (7), p.2089
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Berberine Encapsulated Lecithin–Chitosan Nanoparticles as Innovative Wound Healing Agent in Type II Diabetes
Author / Creator:Panda, Dibya Sundar ; Eid, Hussein M. ; Elkomy, Mohammed H. ; Khames, Ahmed ; Hassan, Randa M. ; Abo El-Ela, Fatma I. ; Yassin, Heba A.
Publisher:Basel: MDPI AG
Journal title:Pharmaceutics, 2021-08, Vol.13 (8), p.1197
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Novasomes as Nano-Vesicular Carriers to Enhance Topical Delivery of Fluconazole: A New Approach to Treat Fungal Infections
Author / Creator:Fatima, Iman ; Rasul, Akhtar ; Shah, Shahid ; Saadullah, Malik ; Islam, Nayyer ; Khames, Ahmed ; Salawi, Ahmad ; Ahmed, Muhammad Masood ; Almoshari, Yosif ; Abbas, Ghulam ; Abourehab, Mohammed A S ; Mehmood Khan, Sajid ; Chauhdary, Zunera ; Alshamrani, Meshal ; Namazi, Nader Ibrahim ; Naguib, Demiana M
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-05, Vol.27 (9), p.2936
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Selected Class of Enamides Bearing Nitro Functionality as Dual-Acting with Highly Selective Monoamine Oxidase-B and BACE1 Inhibitors
Author / Creator:Venkidath, Anusree ; Oh, Jong Min ; Dev, Sanal ; Amin, Elham ; Rasheed, Shebina P. ; Vengamthodi, Ajeesh ; Gambacorta, Nicola ; Khames, Ahmed ; Abdelgawad, Mohamed A. ; George, Ginson ; Nicolotti, Orazio ; Kim, Hoon ; Mathew, Bijo
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-10, Vol.26 (19), p.6004
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Treatment of Inflammatory Bowel Disease by Using Curcumin-Containing Self-Microemulsifying Delivery System: Macroscopic and Microscopic Analysis
Author / Creator:Ameer, Nabeela ; Hanif, Muhammad ; Abbas, Ghulam ; Azeem, Muhammad ; Mahmood, Khalid ; Shahwar, Dure ; Khames, Ahmed ; Eissa, Essam Mohamed ; Daihom, Baher
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2024-11, Vol.16 (11), p.1406
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Development of Halogenated Pyrazolines as Selective Monoamine Oxidase-B Inhibitors: Deciphering via Molecular Dynamics Approach
Author / Creator:Nair, Aathira Sujathan ; Oh, Jong-Min ; Koyiparambath, Vishal Payyalot ; Kumar, Sunil ; Sudevan, Sachithra Thazhathuveedu ; Soremekun, Opeyemi ; Soliman, Mahmoud E. ; Khames, Ahmed ; Abdelgawad, Mohamed A. ; Pappachen, Leena K. ; Mathew, Bijo ; Kim, Hoon
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-05, Vol.26 (11), p.3264
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Multifunctional Isosteric Pyridine Analogs-Based 2-Aminothiazole: Design, Synthesis, and Potential Phosphodiesterase-5 Inhibitory Activity
Author / Creator:Hussein, Abdel Haleem M ; Khames, Ahmed A ; El-Adasy, Abu-Bakr A ; Atalla, Ahmed A ; Abdel-Rady, Mohamed ; Hassan, Mohamed I A ; Abou-Salim, Mahrous A ; Elshaier, Yaseen A M M ; Barakat, Assem
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-02, Vol.26 (4), p.902
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Antibacterial and Wound-Healing Activities of Statistically Optimized Nitrofurazone- and Lidocaine-Loaded Silica Microspheres by the Box-Behnken Design
Author / Creator:Khan, Hafeez Ullah ; Nasir, Fahmeed ; Maheen, Safirah ; Shafqat, Syed Salman ; Shah, Shahid ; Khames, Ahmed ; Ghoneim, Mohammed M ; Abbas, Ghulam ; Shabbir, Saleha ; Abdelgawad, Mohamed A ; Abourehab, Mohammad A S ; Irfan, Amna ; El Sisi, Amani M
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-04, Vol.27 (8), p.2532
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ArticlesPeer ReviewedFull Text
Tolmetin Sodium Fast Dissolving Tablets for Rheumatoid Arthritis Treatment: Preparation and Optimization Using Box-Behnken Design and Response Surface Methodology
Author / Creator:Elsayed, Mahmoud M A ; Aboelez, Moustafa O ; Elsadek, Bakheet E M ; Sarhan, Hatem A ; Khaled, Khaled Ali ; Belal, Amany ; Khames, Ahmed ; Hassan, Yasser A ; Abdel-Rheem, Amany A ; Elkaeed, Eslam B ; Raafat, Mohamed ; Elsadek, Mahmoud Elkot Mostafa
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2022-04, Vol.14 (4), p.880
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ArticlesPeer ReviewedFull Text
Sesame Oil-Based Nanostructured Lipid Carriers of Nicergoline, Intranasal Delivery System for Brain Targeting of Synergistic Cerebrovascular Protection
Author / Creator:Abourehab, Mohammed A S ; Khames, Ahmed ; Genedy, Samar ; Mostafa, Shahin ; Khaleel, Mohammad A ; Omar, Mahmoud M ; El Sisi, Amani M
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2021-04, Vol.13 (4), p.581
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Trimethoxylated Halogenated Chalcones as Dual Inhibitors of MAO-B and BACE-1 for the Treatment of Neurodegenerative Disorders
Author / Creator:Vishal, Vishal Payyalot ; Oh, Jong Min ; Khames, Ahmed ; Abdelgawad, Mohamed A. ; Nair, Aathira Sujathan ; Nath, Lekshmi R. ; Gambacorta, Nicola ; Ciriaco, Fulvio ; Nicolotti, Orazio ; Kim, Hoon ; Mathew, Bijo
Publisher:Basel: MDPI AG
Journal title:Pharmaceutics, 2021-06, Vol.13 (6), p.850
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Enhancement of the Solubility and Bioavailability of Pitavastatin through a Self-Nanoemulsifying Drug Delivery System (SNEDDS)
Author / Creator:Ashfaq, Mehran ; Shah, Shahid ; Rasul, Akhtar ; Hanif, Muhammad ; Khan, Hafeez Ullah ; Khames, Ahmed ; Abdelgawad, Mohamed A ; Ghoneim, Mohammed M ; Ali, Muhammad Yasir ; Abourehab, Mohammad A S ; Maheen, Safirah ; Iqbal, Omeira ; Abbas, Ghulam ; El Sisi, Amani M
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2022-02, Vol.14 (3), p.482
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Development and Characterization of Eudragit ® EPO-Based Solid Dispersion of Rosuvastatin Calcium to Foresee the Impact on Solubility, Dissolution and Antihyperlipidemic Activity
Author / Creator:Inam, Sana ; Irfan, Muhammad ; Lali, Noor Ul Ain ; Khalid Syed, Haroon ; Asghar, Sajid ; Khan, Ikram Ullah ; Khan, Salah-Ud-Din ; Iqbal, Muhammad Shahid ; Zaheer, Imran ; Khames, Ahmed ; Abou-Taleb, Heba A ; Abourehab, Mohammad A S
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2022-04, Vol.15 (4), p.492
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Development of omega-3 loxoprofen-loaded nanoemulsion to limit the side effect associated with NSAIDs in treatment of tooth pain
Author / Creator:Hosny, Khaled M. ; Sindi, Amal M. ; Alkhalidi, Hala M. ; Kurakula, Mallesh ; Hassan, Amira H. ; Bakhaidar, Rana B. ; Abualsunun, Walaa A. ; Almehmady, Alshaimaa M. ; Khames, Ahmed ; Rizg, Waleed Y. ; Khallaf, Rasha A. ; Alruwaili, Nabil K. ; Alhakamy, Nabil A.
Publisher:England: Taylor & Francis
Journal title:Drug delivery, 2021-01, Vol.28 (1), p.741-751
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Glimepiride-Loaded Nanoemulgel; Development, In Vitro Characterization, Ex Vivo Permeation and In Vivo Antidiabetic Evaluation
Author / Creator:Razzaq, Fizza Abdul ; Asif, Muhammad ; Asghar, Sajid ; Iqbal, Muhammad Shahid ; Khan, Ikram Ullah ; Khan, Salah-Ud-Din ; Irfan, Muhammad ; Syed, Haroon Khalid ; Khames, Ahmed ; Mahmood, Hira ; Ibrahim, Asim Y. ; El Sisi, Amani M.
Publisher:Basel: MDPI AG
Journal title:Cells (Basel, Switzerland), 2021-09, Vol.10 (9), p.2404
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Replacement of Chalcone-Ethers with Chalcone-Thioethers as Potent and Highly Selective Monoamine Oxidase-B Inhibitors and Their Protein-Ligand Interactions
Author / Creator:Mathew, Bijo ; Oh, Jong Min ; Khames, Ahmed ; Abdelgawad, Mohamed A. ; Rangarajan, T. M. ; Nath, Lekshmi R. ; Agoni, Clement ; Soliman, Mahmoud E. S. ; Mathew, Githa Elizabeth ; Kim, Hoon
Publisher:Basel: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2021-11, Vol.14 (11), p.1148
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Improved Bioavailability of Ebastine through Development of Transfersomal Oral Films
Author / Creator:Islam, Nayyer ; Irfan, Muhammad ; Zahoor, Ameer Fawad ; Iqbal, Muhammad Shahid ; Syed, Haroon Khalid ; Khan, Ikram Ullah ; Rasul, Akhtar ; Khan, Salah-Ud-Din ; Alqahtani, Alaa M. ; Ikram, Muzzamil ; Abdul Qayyum, Muhammad ; Khames, Ahmed ; Inam, Sana ; Abourehab, Mohammed A. S.
Publisher:Basel: MDPI AG
Journal title:Pharmaceutics, 2021-08, Vol.13 (8), p.1315
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Toward the Identification of Natural Antiviral Drug Candidates against Merkel Cell Polyomavirus: Computational Drug Design Approaches
Author / Creator:Asseri, Amer H ; Alam, Md Jahidul ; Alzahrani, Faisal ; Khames, Ahmed ; Pathan, Mohammad Turhan ; Abourehab, Mohammed A S ; Hosawi, Salman ; Ahmed, Rubaiat ; Sultana, Sifat Ara ; Alam, Nazia Fairooz ; Alam, Nafee-Ul ; Alam, Rahat ; Samad, Abdus ; Pokhrel, Sushil ; Kim, Jin Kyu ; Ahammad, Foysal ; Kim, Bonglee ; Tan, Shing Cheng
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2022-04, Vol.15 (5), p.501
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Showing 1 to 20 of 48 results

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Investigation of the effect of solubility increase at the main absorption site on bioavailability of BCS class II drug (risperidone) using liquisolid technique

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Formulation and Characterization of Eplerenone Nanoemulsion Liquisolids, An Oral Delivery System with Higher Release Rate and Improved Bioavailability

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Computational Identification of Druggable Bioactive Compounds from Catharanthus roseus and Avicennia marina against Colorectal Cancer by Targeting Thymidylate Synthase

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Berberine Encapsulated Lecithin–Chitosan Nanoparticles as Innovative Wound Healing Agent in Type II Diabetes

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Novasomes as Nano-Vesicular Carriers to Enhance Topical Delivery of Fluconazole: A New Approach to Treat Fungal Infections

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Selected Class of Enamides Bearing Nitro Functionality as Dual-Acting with Highly Selective Monoamine Oxidase-B and BACE1 Inhibitors

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Treatment of Inflammatory Bowel Disease by Using Curcumin-Containing Self-Microemulsifying Delivery System: Macroscopic and Microscopic Analysis

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Development of Halogenated Pyrazolines as Selective Monoamine Oxidase-B Inhibitors: Deciphering via Molecular Dynamics Approach

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Multifunctional Isosteric Pyridine Analogs-Based 2-Aminothiazole: Design, Synthesis, and Potential Phosphodiesterase-5 Inhibitory Activity

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Antibacterial and Wound-Healing Activities of Statistically Optimized Nitrofurazone- and Lidocaine-Loaded Silica Microspheres by the Box-Behnken Design

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Tolmetin Sodium Fast Dissolving Tablets for Rheumatoid Arthritis Treatment: Preparation and Optimization Using Box-Behnken Design and Response Surface Methodology

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Sesame Oil-Based Nanostructured Lipid Carriers of Nicergoline, Intranasal Delivery System for Brain Targeting of Synergistic Cerebrovascular Protection

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Trimethoxylated Halogenated Chalcones as Dual Inhibitors of MAO-B and BACE-1 for the Treatment of Neurodegenerative Disorders

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Enhancement of the Solubility and Bioavailability of Pitavastatin through a Self-Nanoemulsifying Drug Delivery System (SNEDDS)

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Development and Characterization of Eudragit ® EPO-Based Solid Dispersion of Rosuvastatin Calcium to Foresee the Impact on Solubility, Dissolution and Antihyperlipidemic Activity

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Development of omega-3 loxoprofen-loaded nanoemulsion to limit the side effect associated with NSAIDs in treatment of tooth pain

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Glimepiride-Loaded Nanoemulgel; Development, In Vitro Characterization, Ex Vivo Permeation and In Vivo Antidiabetic Evaluation

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Replacement of Chalcone-Ethers with Chalcone-Thioethers as Potent and Highly Selective Monoamine Oxidase-B Inhibitors and Their Protein-Ligand Interactions

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Improved Bioavailability of Ebastine through Development of Transfersomal Oral Films

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Toward the Identification of Natural Antiviral Drug Candidates against Merkel Cell Polyomavirus: Computational Drug Design Approaches

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