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The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes a...

The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22de59ffd416471b9dbd2a4adc27aee5

The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular Toxicity

About this item

Full title

The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular Toxicity

Publisher

Switzerland: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2022-02, Vol.27 (4), p.1293

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

A wide variety of oligomeric structures are formed during the aggregation of proteins associated with neurodegenerative diseases. Such soluble oligomers are believed to be key toxic species in the related disorders; therefore, identification of the structural determinants of toxicity is of upmost importance. Here, we analysed toxic oligomers of α-s...

Alternative Titles

Full title

The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular Toxicity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_22de59ffd416471b9dbd2a4adc27aee5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22de59ffd416471b9dbd2a4adc27aee5

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules27041293

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