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CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseu...

CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2342fcd19c9a489d89c6717fe4338e53

CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT

About this item

Full title

CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-03, Vol.13 (1), p.1295-1295, Article 1295

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Type 3 Secretion System (T3SS) is a highly conserved virulence structure that plays an essential role in the pathogenesis of many Gram-negative pathogenic bacteria, including
Pseudomonas aeruginosa
. Exotoxin T (ExoT) is the only T3SS effector protein that is expressed in all T3SS-expressing
P. aeruginosa
strains. Here we show that T3SS...

Alternative Titles

Full title

CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2342fcd19c9a489d89c6717fe4338e53

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2342fcd19c9a489d89c6717fe4338e53

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-28967-5

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