Genome-wide CRISPR screens identify GATA6 as a proviral host factor for SARS-CoV-2 via modulation of...
Genome-wide CRISPR screens identify GATA6 as a proviral host factor for SARS-CoV-2 via modulation of ACE2
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Author / Creator
Israeli, Ma’ayan , Finkel, Yaara , Yahalom-Ronen, Yfat , Paran, Nir , Chitlaru, Theodor , Israeli, Ofir , Cohen-Gihon, Inbar , Aftalion, Moshe , Falach, Reut , Rotem, Shahar , Elia, Uri , Nemet, Ital , Kliker, Limor , Mandelboim, Michal , Beth-Din, Adi , Israely, Tomer , Cohen, Ofer , Stern-Ginossar, Noam and Bercovich-Kinori, Adi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
The global spread of SARS-CoV-2 led to major economic and health challenges worldwide. Revealing host genes essential for infection by multiple variants of SARS-CoV-2 can provide insights into the virus pathogenesis, and facilitate the development of novel therapeutics. Here, employing a genome-scale CRISPR screen, we provide a comprehensive data-s...
Alternative Titles
Full title
Genome-wide CRISPR screens identify GATA6 as a proviral host factor for SARS-CoV-2 via modulation of ACE2
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_234527f794a946638ae72a22b7b11809
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_234527f794a946638ae72a22b7b11809
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-29896-z
