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Mass spectrometry reveals the chemistry of formaldehyde cross-linking in structured proteins

Mass spectrometry reveals the chemistry of formaldehyde cross-linking in structured proteins

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_241e25d8cf7443558ebf3920295f87b0

Mass spectrometry reveals the chemistry of formaldehyde cross-linking in structured proteins

About this item

Full title

Mass spectrometry reveals the chemistry of formaldehyde cross-linking in structured proteins

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-06, Vol.11 (1), p.3128-3128, Article 3128

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Whole-cell cross-linking coupled to mass spectrometry is one of the few tools that can probe protein–protein interactions in intact cells. A very attractive reagent for this purpose is formaldehyde, a small molecule which is known to rapidly penetrate into all cellular compartments and to preserve the protein structure. In light of these benefits,...

Alternative Titles

Full title

Mass spectrometry reveals the chemistry of formaldehyde cross-linking in structured proteins

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_241e25d8cf7443558ebf3920295f87b0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_241e25d8cf7443558ebf3920295f87b0

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-16935-w

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