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Architecture of the U6 snRNP reveals specific recognition of 3′-end processed U6 snRNA

Architecture of the U6 snRNP reveals specific recognition of 3′-end processed U6 snRNA

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_247c7acfc7f34bfb91ac25bc3292cfd3

Architecture of the U6 snRNP reveals specific recognition of 3′-end processed U6 snRNA

About this item

Full title

Architecture of the U6 snRNP reveals specific recognition of 3′-end processed U6 snRNA

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-05, Vol.9 (1), p.1749-11, Article 1749

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The spliceosome removes introns from precursor messenger RNA (pre-mRNA) to produce mature mRNA. Prior to catalysis, spliceosomes are assembled de novo onto pre-mRNA substrates. During this assembly process, U6 small nuclear RNA (snRNA) undergoes extensive structural remodeling. The early stages of this remodeling process are chaperoned by U6 snRNP...

Alternative Titles

Full title

Architecture of the U6 snRNP reveals specific recognition of 3′-end processed U6 snRNA

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_247c7acfc7f34bfb91ac25bc3292cfd3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_247c7acfc7f34bfb91ac25bc3292cfd3

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-04145-4

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