Interpreting polygenic score effects in sibling analysis
Interpreting polygenic score effects in sibling analysis
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Researchers often claim that sibling analysis can be used to separate causal genetic effects from the assortment of biases that contaminate most downstream genetic studies (e.g. polygenic score predictors). Indeed, typical results from sibling analysis show large (>50%) attenuations in the associations between polygenic scores and phenotypes compar...
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Full title
Interpreting polygenic score effects in sibling analysis
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TN_cdi_doaj_primary_oai_doaj_org_article_24803cb165f64c4485f4c3931d09439a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_24803cb165f64c4485f4c3931d09439a
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0282212
