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Greater tau load and reduced cortical thickness in APOE ε4-negative Alzheimer's disease: a cohort st...

Greater tau load and reduced cortical thickness in APOE ε4-negative Alzheimer's disease: a cohort st...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_24aa7163c24f462a8db01f0b3da2cef2

Greater tau load and reduced cortical thickness in APOE ε4-negative Alzheimer's disease: a cohort study

About this item

Full title

Greater tau load and reduced cortical thickness in APOE ε4-negative Alzheimer's disease: a cohort study

Publisher

England: BioMed Central

Journal title

Alzheimer's research & therapy, 2018-08, Vol.10 (1), p.77-12, Article 77

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Alzheimer's disease is characterized by aggregated β-amyloid and tau proteins, but the clinical presentations and patterns of brain atrophy vary substantially. A part of this heterogeneity may be linked to the risk allele APOE ε4. The spread of tau pathology is related to atrophy and cognitive decline, but little data exist on the effects of APOE ε...

Alternative Titles

Full title

Greater tau load and reduced cortical thickness in APOE ε4-negative Alzheimer's disease: a cohort study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_24aa7163c24f462a8db01f0b3da2cef2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_24aa7163c24f462a8db01f0b3da2cef2

Other Identifiers

ISSN

1758-9193

E-ISSN

1758-9193

DOI

10.1186/s13195-018-0403-x

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