Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor
Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor
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Author / Creator
Wang, Yue , Guo, Shimeng , Zhuang, Youwen , Yun, Ying , Xu, Peiyu , He, Xinheng , Guo, Jia , Yin, Wanchao , Xu, H. Eric , Xie, Xin and Jiang, Yi
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Ghrelin, also called “the hunger hormone”, is a gastric peptide hormone that regulates food intake, body weight, as well as taste sensation, reward, cognition, learning and memory. One unique feature of ghrelin is its acylation, primarily with an octanoic acid, which is essential for its binding and activation of the ghrelin receptor, a G protein-c...
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Full title
Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor
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TN_cdi_doaj_primary_oai_doaj_org_article_24e534c788b94b1ebb4dd46fb7bb7dbf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_24e534c788b94b1ebb4dd46fb7bb7dbf
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25364-2
