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ArticlesPeer ReviewedFull Text
Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin
Author / Creator:Yin, Wanchao ; Luan, Xiaodong ; Li, Zhihai ; Zhou, Ziwei ; Wang, Qingxing ; Gao, Minqi ; Wang, Xiaoxi ; Zhou, Fulai ; Shi, Jingjing ; You, Erli ; Liu, Mingliang ; Wang, Qingxia ; Jiang, Yi ; Jiang, Hualiang ; Xiao, Gengfu ; Zhang, Leike ; Yu, Xuekui ; Zhang, Shuyang ; Eric Xu, H.
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2021-03, Vol.28 (3), p.319-325
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Amyloid beta： structure, biology and structure-based therapeutic development
Author / Creator:Chen, Guo-fang ; Xu, Ting-hai ; Yan, Yan ; Zhou, Yu-ren ; Jiang, Yi ; Melcher, Karsten ; Xu, H Eric
Publisher:London: Nature Publishing Group UK
Journal title:Acta pharmacologica Sinica, 2017-09, Vol.38 (9), p.1205-1235
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Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase
Author / Creator:Byun, Sangwon ; Seok, Sunmi ; Kim, Young-Chae ; Zhang, Yang ; Yau, Peter ; Iwamori, Naoki ; Xu, H. Eric ; Ma, Jian ; Kemper, Byron ; Kemper, Jongsook Kim
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-02, Vol.11 (1), p.807-807, Article 807
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Structure and Physiological Regulation of AMPK
Author / Creator:Yan, Yan ; Zhou, X. Edward ; Xu, H. Eric ; Melcher, Karsten
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2018-11, Vol.19 (11), p.3534
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Structure and dynamics of the active human parathyroid hormone receptor-1
Author / Creator:Zhao, Li-Hua ; Ma, Shanshan ; Sutkeviciute, Ieva ; Shen, Dan-Dan ; Zhou, X. Edward ; de Waal, Parker W. ; Li, Chen-Yao ; Kang, Yanyong ; Clark, Lisa J. ; Jean-Alphonse, Frederic G. ; White, Alex D. ; Yang, Dehua ; Dai, Antao ; Cai, Xiaoqing ; Chen, Jian ; Li, Cong ; Jiang, Yi ; Watanabe, Tomoyuki ; Gardella, Thomas J. ; Melcher, Karsten ; Wang, Ming-Wei ; Vilardaga, Jean-Pierre ; Xu, H. Eric ; Zhang, Yan
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2019-04, Vol.364 (6436), p.148-153
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A complex structure of arrestin-2 bound to a G protein-coupled receptor
Author / Creator:Yin, Wanchao ; Li, Zhihai ; Jin, Mingliang ; Yin, Yu-Ling ; de Waal, Parker W. ; Pal, Kuntal ; Yin, Yanting ; Gao, Xiang ; He, Yuanzheng ; Gao, Jing ; Wang, Xiaoxi ; Zhang, Yan ; Zhou, Hu ; Melcher, Karsten ; Jiang, Yi ; Cong, Yao ; Edward Zhou, X. ; Yu, Xuekui ; Eric Xu, H.
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2019-12, Vol.29 (12), p.971-983
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Structural basis of leukotriene B4 receptor 1 activation
Author / Creator:Wang, Na ; He, Xinheng ; Zhao, Jing ; Jiang, Hualiang ; Cheng, Xi ; Xia, Yu ; Eric Xu, H. ; He, Yuanzheng
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-03, Vol.13 (1), p.1156-1156, Article 1156
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Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2
Author / Creator:Zhuang, Youwen ; Wang, Lei ; Guo, Jia ; Sun, Dapeng ; Wang, Yue ; Liu, Weiyi ; Xu, H. Eric ; Zhang, Cheng
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-02, Vol.13 (1), p.1054-1054, Article 1054
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Structural basis of human α7 nicotinic acetylcholine receptor activation
Author / Creator:Zhao, Yue ; Liu, Sanling ; Zhou, Yingxin ; Zhang, Mengge ; Chen, Haopeng ; Eric Xu, H. ; Sun, Demeng ; Liu, Lei ; Tian, Changlin
Publisher:Singapore: Springer Singapore
Journal title:Cell research, 2021-06, Vol.31 (6), p.713-716
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Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy
Author / Creator:Duan, Jia ; Shen, Dan-dan ; Zhou, X. Edward ; Bi, Peng ; Liu, Qiu-feng ; Tan, Yang-xia ; Zhuang, You-wen ; Zhang, Hui-bing ; Xu, Pei-yu ; Huang, Si-Jie ; Ma, Shan-shan ; He, Xin-heng ; Melcher, Karsten ; Zhang, Yan ; Xu, H. Eric ; Jiang, Yi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-08, Vol.11 (1), p.4121-4121, Article 4121
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Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor
Author / Creator:Wang, Yue ; Guo, Shimeng ; Zhuang, Youwen ; Yun, Ying ; Xu, Peiyu ; He, Xinheng ; Guo, Jia ; Yin, Wanchao ; Xu, H. Eric ; Xie, Xin ; Jiang, Yi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-08, Vol.12 (1), p.5064-5064, Article 5064
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Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors
Author / Creator:Zhao, Fenghui ; Zhou, Qingtong ; Cong, Zhaotong ; Hang, Kaini ; Zou, Xinyu ; Zhang, Chao ; Chen, Yan ; Dai, Antao ; Liang, Anyi ; Ming, Qianqian ; Wang, Mu ; Chen, Li-Nan ; Xu, Peiyu ; Chang, Rulve ; Feng, Wenbo ; Xia, Tian ; Zhang, Yan ; Wu, Beili ; Yang, Dehua ; Zhao, Lihua ; Xu, H. Eric ; Wang, Ming-Wei
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-02, Vol.13 (1), p.1057-1057, Article 1057
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Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor
Author / Creator:Liu, Qiufeng ; Yang, Dehua ; Zhuang, Youwen ; Croll, Tristan I. ; Cai, Xiaoqing ; Dai, Antao ; He, Xinheng ; Duan, Jia ; Yin, Wanchao ; Ye, Chenyu ; Zhou, Fulai ; Wu, Beili ; Zhao, Qiang ; Xu, H. Eric ; Wang, Ming-Wei ; Jiang, Yi
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2021-12, Vol.17 (12), p.1238-1244
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Synthetic antibodies against BRIL as universal fiducial marks for single−particle cryoEM structure determination of membrane proteins
Author / Creator:Mukherjee, Somnath ; Erramilli, Satchal K. ; Ammirati, Mark ; Alvarez, Frances J. D. ; Fennell, Kimberly F. ; Purdy, Michael D. ; Skrobek, Blazej M. ; Radziwon, Katarzyna ; Coukos, John ; Kang, Yanyong ; Dutka, Przemysław ; Gao, Xiang ; Qiu, Xiayang ; Yeager, Mark ; Eric Xu, H. ; Han, Seungil ; Kossiakoff, Anthony A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-03, Vol.11 (1), p.1598-1598, Article 1598
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Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2
Author / Creator:Xie, Yuanchao ; Yin, Wanchao ; Zhang, Yumin ; Shang, Weijuan ; Wang, Zhen ; Luan, Xiaodong ; Tian, Guanghui ; Aisa, Haji A. ; Xu, Yechun ; Xiao, Gengfu ; Li, Jia ; Jiang, Hualiang ; Zhang, Shuyang ; Zhang, Leike ; Xu, H. Eric ; Shen, Jingshan
Publisher:Singapore: Springer Singapore
Journal title:Cell research, 2021-11, Vol.31 (11), p.1212-1214
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Structural basis for the tethered peptide activation of adhesion GPCRs
Author / Creator:Ping, Yu-Qi ; Xiao, Peng ; Yang, Fan ; Zhao, Ru-Jia ; Guo, Sheng-Chao ; Yan, Xu ; Wu, Xiang ; Zhang, Chao ; Lu, Yan ; Zhao, Fenghui ; Zhou, Fulai ; Xi, Yue-Tong ; Yin, Wanchao ; Liu, Feng-Zhen ; He, Dong-Fang ; Zhang, Dao-Lai ; Zhu, Zhong-Liang ; Jiang, Yi ; Du, Lutao ; Feng, Shi-Qing ; Schöneberg, Torsten ; Liebscher, Ines ; Xu, H. Eric ; Sun, Jin-Peng
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-04, Vol.604 (7907), p.763-770
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Structural basis for molecular recognition of folic acid by folate receptors
Author / Creator:Chen, Chen ; Ke, Jiyuan ; Zhou, X. Edward ; Yi, Wei ; Brunzelle, Joseph S. ; Li, Jun ; Yong, Eu-Leong ; Xu, H. Eric ; Melcher, Karsten
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-08, Vol.500 (7463), p.486-489
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Structure of formylpeptide receptor 2-Gi complex reveals insights into ligand recognition and signaling
Author / Creator:Zhuang, Youwen ; Liu, Heng ; Edward Zhou, X. ; Kumar Verma, Ravi ; de Waal, Parker W. ; Jang, Wonjo ; Xu, Ting-Hai ; Wang, Lei ; Meng, Xing ; Zhao, Gongpu ; Kang, Yanyong ; Melcher, Karsten ; Fan, Hao ; Lambert, Nevin A. ; Eric Xu, H. ; Zhang, Cheng
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-02, Vol.11 (1), p.1-12, Article 885
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Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors
Author / Creator:Duan, Jia ; Shen, Dan-Dan ; Zhao, Tingting ; Guo, Shimeng ; He, Xinheng ; Yin, Wanchao ; Xu, Peiyu ; Ji, Yujie ; Chen, Li-Nan ; Liu, Jinyu ; Zhang, Huibing ; Liu, Qiufeng ; Shi, Yi ; Cheng, Xi ; Jiang, Hualiang ; Eric Xu, H. ; Zhang, Yan ; Xie, Xin ; Jiang, Yi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-03, Vol.13 (1), p.1364-1364, Article 1364
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Androgen receptor： structure, role in prostate cancer and drug discovery
Author / Creator:Tan, MH Eileen ; Li, Jun ; Xu, H Eric ; Melcher, Karsten ; Yong, Eu-leong
Publisher:London: Nature Publishing Group UK
Journal title:Acta pharmacologica Sinica, 2015-01, Vol.36 (1), p.3-23
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Showing 1 to 20 of 229 results

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Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin

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Amyloid beta： structure, biology and structure-based therapeutic development

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Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase

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Structure and Physiological Regulation of AMPK

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Structure and dynamics of the active human parathyroid hormone receptor-1

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A complex structure of arrestin-2 bound to a G protein-coupled receptor

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Structural basis of leukotriene B4 receptor 1 activation

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Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2

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Structural basis of human α7 nicotinic acetylcholine receptor activation

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Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy

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Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor

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Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors

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Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor

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Synthetic antibodies against BRIL as universal fiducial marks for single−particle cryoEM structure determination of membrane proteins

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Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2

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Structural basis for the tethered peptide activation of adhesion GPCRs

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Structural basis for molecular recognition of folic acid by folate receptors

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Structure of formylpeptide receptor 2-Gi complex reveals insights into ligand recognition and signaling

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Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors

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Androgen receptor： structure, role in prostate cancer and drug discovery

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