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RTN3 regulates collagen biosynthesis and profibrotic macrophage differentiation to promote pulmonary...

RTN3 regulates collagen biosynthesis and profibrotic macrophage differentiation to promote pulmonary...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_24ebfeaf490f4fa6a49005e784c51862

RTN3 regulates collagen biosynthesis and profibrotic macrophage differentiation to promote pulmonary fibrosis via interacting with CRTH2

About this item

Full title

RTN3 regulates collagen biosynthesis and profibrotic macrophage differentiation to promote pulmonary fibrosis via interacting with CRTH2

Publisher

England: Springer

Journal title

Molecular Medicine, 2025-02, Vol.31 (1), p.63-14, Article 63

Language

English

Formats

Publication information

Publisher

England: Springer

More information

Scope and Contents

Contents

As an endoplasmic reticulum (ER) protein, Reticulum 3 (RTN3) has been reported to play a crucial role in neurodegenerative diseases, lipid metabolism, and chronic kidney disease. The involvement of RTN3 in idiopathic pulmonary fibrosis (IPF), a progressive and fatal interstitial lung disease, remains unexplored.
In this study, we explored the ro...

Alternative Titles

Full title

RTN3 regulates collagen biosynthesis and profibrotic macrophage differentiation to promote pulmonary fibrosis via interacting with CRTH2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_24ebfeaf490f4fa6a49005e784c51862

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_24ebfeaf490f4fa6a49005e784c51862

Other Identifiers

ISSN

1528-3658,1076-1551

E-ISSN

1528-3658

DOI

10.1186/s10020-025-01119-3

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