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KIF1C facilitates retrograde transport of lysosomes through Hook3 and dynein

KIF1C facilitates retrograde transport of lysosomes through Hook3 and dynein

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_25808fce8c024d70989388fc2a7c7a29

KIF1C facilitates retrograde transport of lysosomes through Hook3 and dynein

About this item

Full title

KIF1C facilitates retrograde transport of lysosomes through Hook3 and dynein

Publisher

London: Nature Publishing Group UK

Journal title

Communications biology, 2024-10, Vol.7 (1), p.1305-12, Article 1305

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Lysosomes, crucial cellular organelles, undergo bidirectional transport along microtubules, mediated by motor proteins such as cytoplasmic dynein-1 (dynein) and various kinesins. While the kinesin-3 family member KIF1C is established in mediating anterograde vesicle transport, its role in lysosomal transport remains unclear. Our study reveals that...

Alternative Titles

Full title

KIF1C facilitates retrograde transport of lysosomes through Hook3 and dynein

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_25808fce8c024d70989388fc2a7c7a29

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_25808fce8c024d70989388fc2a7c7a29

Other Identifiers

ISSN

2399-3642

E-ISSN

2399-3642

DOI

10.1038/s42003-024-07023-6

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