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Association between herpes simplex virus infection and Alzheimer’s disease biomarkers: analysis with...

Association between herpes simplex virus infection and Alzheimer’s disease biomarkers: analysis with...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_260cbbe1d526489bb4ed348f96fa03ad

Association between herpes simplex virus infection and Alzheimer’s disease biomarkers: analysis within the MAPT trial

About this item

Full title

Association between herpes simplex virus infection and Alzheimer’s disease biomarkers: analysis within the MAPT trial

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2025-01, Vol.15 (1), p.2362-10, Article 2362

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

In vitro and animal studies have suggested that inoculation with herpes simplex virus 1 (HSV-1) can lead to amyloid deposits, hyperphosphorylation of tau, and/or neuronal loss. Here, we studied the association between HSV-1 and Alzheimer’s disease biomarkers in humans. Our sample included 182 participants at risk of cognitive decline from the Multi...

Alternative Titles

Full title

Association between herpes simplex virus infection and Alzheimer’s disease biomarkers: analysis within the MAPT trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_260cbbe1d526489bb4ed348f96fa03ad

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_260cbbe1d526489bb4ed348f96fa03ad

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-84583-x