NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle
NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle
About this item
Full title
Author / Creator
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Advanced Light Source (ALS) , Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS) , Kosciuk, Tatsiana , Price, Ian R. , Zhang, Xiaoyu , Zhu, Chengliang , Johnson, Kayla N. , Zhang, Shuai , Halaby, Steve L. , Komaniecki, Garrison P. , Yang, Min , DeHart, Caroline J. , Thomas, Paul M. , Kelleher, Neil L. , Fromme, J. Christopher and Lin, Hening
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Lysine fatty acylation in mammalian cells was discovered nearly three decades ago, yet the enzymes catalyzing it remain unknown. Unexpectedly, we find that human N-terminal glycine myristoyltransferases (NMT) 1 and 2 can efficiently myristoylate specific lysine residues. They modify ADP-ribosylation factor 6 (ARF6) on lysine 3 allowing it to remain...
Alternative Titles
Full title
NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle
Authors, Artists and Contributors
Author / Creator
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Kosciuk, Tatsiana
Price, Ian R.
Zhang, Xiaoyu
Zhu, Chengliang
Johnson, Kayla N.
Zhang, Shuai
Halaby, Steve L.
Komaniecki, Garrison P.
Yang, Min
DeHart, Caroline J.
Thomas, Paul M.
Kelleher, Neil L.
Fromme, J. Christopher
Lin, Hening
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2680a250e1e54ba7aecb1d6f4993fea7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2680a250e1e54ba7aecb1d6f4993fea7
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-14893-x
