ARID1A safeguards the canalization of the cell fate decision during osteoclastogenesis
ARID1A safeguards the canalization of the cell fate decision during osteoclastogenesis
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Author / Creator
Du, Jiahui , Liu, Yili , Sun, Jinrui , Yao, Enhui , Xu, Jingyi , Wu, Xiaolin , Xu, Ling , Zhou, Mingliang , Yang, Guangzheng and Jiang, Xinquan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Chromatin remodeler ARID1A regulates gene transcription by modulating nucleosome positioning and chromatin accessibility. While ARID1A-mediated stage and lineage-restricted gene regulation during cell fate canalization remains unresolved. Using osteoclastogenesis as a model, we show that ARID1A transcriptionally safeguards the osteoclast (OC) fate...
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Full title
ARID1A safeguards the canalization of the cell fate decision during osteoclastogenesis
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_27e2611de8c34960b980f0c207f51176
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_27e2611de8c34960b980f0c207f51176
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-50225-z