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ARID1A safeguards the canalization of the cell fate decision during osteoclastogenesis

ARID1A safeguards the canalization of the cell fate decision during osteoclastogenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_27e2611de8c34960b980f0c207f51176

ARID1A safeguards the canalization of the cell fate decision during osteoclastogenesis

About this item

Full title

ARID1A safeguards the canalization of the cell fate decision during osteoclastogenesis

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-07, Vol.15 (1), p.5994-20, Article 5994

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Chromatin remodeler ARID1A regulates gene transcription by modulating nucleosome positioning and chromatin accessibility. While ARID1A-mediated stage and lineage-restricted gene regulation during cell fate canalization remains unresolved. Using osteoclastogenesis as a model, we show that ARID1A transcriptionally safeguards the osteoclast (OC) fate...

Alternative Titles

Full title

ARID1A safeguards the canalization of the cell fate decision during osteoclastogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_27e2611de8c34960b980f0c207f51176

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_27e2611de8c34960b980f0c207f51176

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-50225-z

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