Nestin-dependent mitochondria-ER contacts define stem Leydig cell differentiation to attenuate male...
Nestin-dependent mitochondria-ER contacts define stem Leydig cell differentiation to attenuate male reproductive ageing
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Author / Creator
Yao, Senyu , Wei, Xiaoyue , Deng, Wenrui , Wang, Boyan , Cai, Jianye , Huang, Yinong , Lai, Xiaofan , Qiu, Yuan , Wang, Yi , Guan, Yuanjun and Wang, Jiancheng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Male reproductive system ageing is closely associated with deficiency in testosterone production due to loss of functional Leydig cells, which are differentiated from stem Leydig cells (SLCs). However, the relationship between SLC differentiation and ageing remains unknown. In addition, active lipid metabolism during SLC differentiation in the repr...
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Full title
Nestin-dependent mitochondria-ER contacts define stem Leydig cell differentiation to attenuate male reproductive ageing
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2845439343764e1fba6f73eab2348679
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2845439343764e1fba6f73eab2348679
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-31755-w
