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Role of SH3GLB1 in the regulation of CD133 expression in GBM cells

Role of SH3GLB1 in the regulation of CD133 expression in GBM cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_28fd7d57eb0d4cf989f662cfd0c58b15

Role of SH3GLB1 in the regulation of CD133 expression in GBM cells

About this item

Full title

Role of SH3GLB1 in the regulation of CD133 expression in GBM cells

Publisher

England: BioMed Central Ltd

Journal title

BMC cancer, 2023-07, Vol.23 (1), p.713-713, Article 713

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Glioblastoma (GBM), a malignant brain tumor, has poor survival outcomes due to recurrence or drug resistance. We found that SH3GLB1 is a crucial factor for cells to evade temozolomide (TMZ) cytotoxicity through autophagy-mediated oxidative phosphorylation, which is associated with CD133 levels. Therefore, we propose that SH3GLB1 participate in the...

Alternative Titles

Full title

Role of SH3GLB1 in the regulation of CD133 expression in GBM cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_28fd7d57eb0d4cf989f662cfd0c58b15

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_28fd7d57eb0d4cf989f662cfd0c58b15

Other Identifiers

ISSN

1471-2407

E-ISSN

1471-2407

DOI

10.1186/s12885-023-11211-8

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