Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells
Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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MR1-restricted T (MR1T) cells recognize microbial small molecule metabolites presented on the MHC Class I-like molecule MR1 and have been implicated in early effector responses to microbial infection. As a result, there is considerable interest in identifying chemical properties of metabolite ligands that permit recognition by MR1T cells, for consi...
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Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells
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TN_cdi_doaj_primary_oai_doaj_org_article_2922d25154b844d9be6d978cad284414
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2922d25154b844d9be6d978cad284414
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-26259-y