Log in to save to my catalogue

Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells

Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2922d25154b844d9be6d978cad284414

Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells

About this item

Full title

Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-12, Vol.12 (1), p.22539-16, Article 22539

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

MR1-restricted T (MR1T) cells recognize microbial small molecule metabolites presented on the MHC Class I-like molecule MR1 and have been implicated in early effector responses to microbial infection. As a result, there is considerable interest in identifying chemical properties of metabolite ligands that permit recognition by MR1T cells, for consi...

Alternative Titles

Full title

Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2922d25154b844d9be6d978cad284414

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2922d25154b844d9be6d978cad284414

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-26259-y

How to access this item