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Newsletter articlesFull Text
INTERNATIONAL PATENT: OREGON HEALTH SCIENCE UNIVERSITY, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, POU, SOVITJ, WINTER, ROLF, W., RISCOE, MICHAEL, J., DOGGETT,...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2021
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ArticlesPeer ReviewedFull Text
Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses
Author / Creator:Sali, Tina M. ; Pryke, Kara M. ; Abraham, Jinu ; Liu, Andrew ; Archer, Iris ; Broeckel, Rebecca ; Staverosky, Julia A. ; Smith, Jessica L. ; Al-Shammari, Ahmed ; Amsler, Lisi ; Sheridan, Kayla ; Nilsen, Aaron ; Streblow, Daniel N. ; DeFilippis, Victor R.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2015-12, Vol.11 (12), p.e1005324-e1005324
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ArticlesPeer ReviewedFull Text
Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis
Author / Creator:Doggett, J. Stone ; Nilsen, Aaron ; Forquer, Isaac ; Wegmann, Keith W ; Jones-Brando, Lorraine ; Yolken, Robert H ; Bordón, Claudia ; Charman, Susan A ; Katneni, Kasiram ; Schultz, Tracey ; Burrows, Jeremy N ; Hinrichs, David J ; Meunier, Brigitte ; Carruthers, Vern B ; Riscoe, Michael K
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (39), p.15936-15941
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ArticlesPeer ReviewedFull Text
Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages
Author / Creator:Ke, Hangjun ; Ganesan, Suresh M. ; Dass, Swati ; Morrisey, Joanne M. ; Pou, Sovitj ; Nilsen, Aaron ; Riscoe, Michael K. ; Mather, Michael W. ; Vaidya, Akhil B.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-04, Vol.14 (4), p.e0214023-e0214023
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ArticlesPeer ReviewedFull Text
4′‐Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN
Author / Creator:Jeong, Suh Young ; Hogarth, Penelope ; Placzek, Andrew ; Gregory, Allison M ; Fox, Rachel ; Zhen, Dolly ; Hamada, Jeffrey ; van der Zwaag, Marianne ; Lambrechts, Roald ; Jin, Haihong ; Nilsen, Aaron ; Cobb, Jared ; Pham, Thao ; Gray, Nora ; Ralle, Martina ; Duffy, Megan ; Schwanemann, Leila ; Rai, Puneet ; Freed, Alison ; Wakeman, Katrina ; Woltjer, Randall L ; Sibon, Ody CM ; Hayflick, Susan J
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2019-12, Vol.11 (12), p.e10489-n/a
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ArticlesPeer ReviewedFull Text
Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells
Author / Creator:Jin, Haihong ; Ladd, Nicole A. ; Peev, Andrew M. ; Swarbrick, Gwendolyn M. ; Cansler, Meghan ; Null, Megan ; Boughter, Christopher T. ; McMurtrey, Curtis ; Nilsen, Aaron ; Dobos, Karen M. ; Hildebrand, William H. ; Lewinsohn, Deborah A. ; Adams, Erin J. ; Lewinsohn, David M. ; Harriff, Melanie J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-12, Vol.12 (1), p.22539-16, Article 22539
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ArticlesPeer ReviewedFull Text
Endochin-like quinolone-300 and ELQ-316 inhibit Babesia bovis, B. bigemina, B. caballi and Theileria equi
Author / Creator:Silva, Marta G. ; Bastos, Reginaldo G. ; Stone Doggett, J. ; Riscoe, Michael K. ; Pou, Sovitj ; Winter, Rolf ; Dodean, Rozalia A. ; Nilsen, Aaron ; Suarez, Carlos E.
Publisher:London: BioMed Central Ltd
Journal title:Parasites & vectors, 2020-12, Vol.13 (1), p.1-11, Article 606
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ArticlesPeer ReviewedFull Text
Targeting mitochondria in cancer therapy could provide a basis for the selective anti-cancer activity
Author / Creator:Rozanov, Dmitri ; Cheltsov, Anton ; Nilsen, Aaron ; Boniface, Christopher ; Forquer, Isaac ; Korkola, James ; Gray, Joe ; Tyner, Jeffrey ; Tognon, Cristina E. ; Mills, Gordon B. ; Spellman, Paul
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-03, Vol.14 (3), p.e0205623
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ArticlesPeer ReviewedFull Text
ELQ-331 as a prototype for extremely durable chemoprotection against malaria
Author / Creator:Smilkstein, Martin J. ; Pou, Sovitj ; Krollenbrock, Alina ; Bleyle, Lisa A. ; Dodean, Rozalia A. ; Frueh, Lisa ; Hinrichs, David J. ; Li, Yuexin ; Martinson, Thomas ; Munar, Myrna Y. ; Winter, Rolf W. ; Bruzual, Igor ; Whiteside, Samantha ; Nilsen, Aaron ; Koop, Dennis R. ; Kelly, Jane X. ; Kappe, Stefan H. I. ; Wilder, Brandon K. ; Riscoe, Michael K.
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2019-08, Vol.18 (1), p.291-17, Article 291
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ArticlesPeer ReviewedFull Text
Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters
Author / Creator:Eshleman, Amy J. ; Nagarajan, Shanthi ; Wolfrum, Katherine M. ; Reed, John F. ; Swanson, Tracy L. ; Nilsen, Aaron ; Janowsky, Aaron
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Psychopharmacology, 2019-03, Vol.236 (3), p.939-952
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ArticlesPeer ReviewedFull Text
Divergent metabolic programmes control two populations of MAIT cells that protect the lung
Author / Creator:Riffelmacher, Thomas ; Paynich Murray, Mallory ; Wientjens, Chantal ; Chandra, Shilpi ; Cedillo-Castelán, Viankail ; Chou, Ting-Fang ; McArdle, Sara ; Dillingham, Christopher ; Devereaux, Jordan ; Nilsen, Aaron ; Brunel, Simon ; Lewinsohn, David M ; Hasty, Jeff ; Seumois, Gregory ; Benedict, Christopher A ; Vijayanand, Pandurangan ; Kronenberg, Mitchell
Publisher:London: Nature Publishing Group
Journal title:Nature cell biology, 2023-06, Vol.25 (6), p.877-891
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ArticlesPeer ReviewedFull Text
Improving solubility and oral bioavailability of a novel antimalarial prodrug: comparing spray-dried dispersions with self-emulsifying drug delivery systems
Author / Creator:Potharaju, Suresh ; Mutyam, Shravan Kumar ; Liu, Mingtao ; Green, Carol ; Frueh, Lisa ; Nilsen, Aaron ; Pou, Sovitj ; Winter, Rolf ; Riscoe, Michael K. ; Shankar, Gita
Publisher:England: Taylor & Francis
Journal title:Pharmaceutical development and technology, 2020-05, Vol.25 (5), p.625-639
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ArticlesPeer ReviewedFull Text
Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum
Author / Creator:Ke, Hangjun ; Ganesan, Suresh M ; Dass, Swati ; Morrisey, Joanne M ; Pou, Sovitj ; Nilsen, Aaron ; Riscoe, Michael K ; Mather, Michael W ; Vaidya, Akhil B
Publisher:Public Library of Science
Journal title:PloS one, 2019-04, Vol.14 (4), p.e0214023
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ArticlesFull Text
Babesia duncani as a model organism to study the development, virulence and drug susceptibility of intraerythrocytic parasites in vitro and in vivo
Author / Creator:Choukri Mamoun ; Pal, Anasuya C ; Renard, Isaline ; Singh, Pallavi ; Vydyam, Pratap ; Chiu, Joy E ; Pou, Sovitj ; Winter, Rolf W ; Dodean, Rozalia ; Frueh, Lisa ; Nilsen, Aaron C ; Riscoe, Michael K ; J Stone Doggett
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-12
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ArticlesFull Text
Effective Therapy Targeting Cytochrome bc1 Prevents Babesia Erythrocytic Development and Protects from Lethal Infection
Author / Creator:Chiu, Joy E ; Renard, Isaline ; Anasuya Chattopadhyay Pal ; Singh, Pallavi ; Vydyam, Pratap ; Thekkiniath, Jose ; Kumar, Madelyn ; Shalev Gihaz ; Pou, Sovitj ; Winter, Rolf W ; Dodean, Rozalia ; Nilsen, Aaron ; Riscoe, Michael K ; J Stone Doggett ; Choukri Ben Mamoun
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-04
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ArticlesPeer ReviewedFull Text
Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses: e1005324
Author / Creator:Sali, Tina M ; Pryke, Kara M ; Abraham, Jinu ; Liu, Andrew ; Archer, Iris ; Broeckel, Rebecca ; Staverosky, Julia A ; Smith, Jessica L ; Al-Shammari, Ahmed ; Amsler, Lisi ; Sheridan, Kayla ; Nilsen, Aaron ; Streblow, Daniel N ; DeFilippis, Victor R
Publisher:San Francisco: Public Library of Science
Journal title:PLoS pathogens, 2015-12, Vol.11 (12)
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ArticlesPeer ReviewedFull Text
Mechanism of Action of ELQ-316 Against Toxoplasma gondii: Evidence for Qi Site Inhibition of Cytochrome bc1
Author / Creator:Alday, P. Holland ; Bruzal, Igor ; Pou, Sovitj ; Nilsen, Aaron ; Riscoe, Michael K ; Doggett, Joseph
Publisher:Oxford: Oxford University Press
Journal title:Open forum infectious diseases, 2016-12, Vol.3 (suppl_1)
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ArticlesFull Text
Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells
Author / Creator:Jin, Haihong ; Ladd, Nicole A. ; Peev, Andrew M. ; Swarbrick, Gwendolyn M. ; Cansler, Meghan ; Null, Megan ; Boughter, Christopher T. ; McMurtrey, Curtis ; Nilsen, Aaron ; Dobos, Karen M. ; Hildebrand, William H. ; Lewinsohn, Deborah A. ; Adams, Erin J. ; Lewinsohn, David M. ; Harriff, Melanie J.
Publisher:Cold Spring Harbor Laboratory
Journal title:bioRxiv, 2022-05
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Web ResourcesFull Text
Endochin-like quinolone-300 and ELQ-316 inhibit Babesia bovis, B. bigemina, B. caballi and Theileria equi
Author / Creator:Silva, Marta G ; Bastos, Reginaldo G ; J. Stone Doggett ; Riscoe, Michael K ; Pou, Sovitj ; Winter, Rolf ; Dodean, Rozalia A ; Nilsen, Aaron ; Suarez, Carlos E
Publisher:Durham: Research Square
Journal title:Parasites & Vectors, 2020
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ArticlesFull Text
Targeting mitochondria in cancer therapy could provide a basis for the selective anti-cancer activity
Author / Creator:Rozanov, Dmitri ; Cheltsov, Anton ; Nilsen, Aaron ; Boniface, Christopher ; Korkola, James ; Gray, Joe ; Tyner, Jeffrey ; Tognon, Cristina E ; Mills, Gordon B ; Spellman, Paul
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2018-10
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INTERNATIONAL PATENT: OREGON HEALTH SCIENCE UNIVERSITY, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, POU, SOVITJ, WINTER, ROLF, W., RISCOE, MICHAEL, J., DOGGETT,...

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Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses

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Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis

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Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages

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4′‐Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN

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Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells

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Endochin-like quinolone-300 and ELQ-316 inhibit Babesia bovis, B. bigemina, B. caballi and Theileria equi

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Targeting mitochondria in cancer therapy could provide a basis for the selective anti-cancer activity

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ELQ-331 as a prototype for extremely durable chemoprotection against malaria

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Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters

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Divergent metabolic programmes control two populations of MAIT cells that protect the lung

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Improving solubility and oral bioavailability of a novel antimalarial prodrug: comparing spray-dried dispersions with self-emulsifying drug delivery systems

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Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum

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Babesia duncani as a model organism to study the development, virulence and drug susceptibility of intraerythrocytic parasites in vitro and in vivo

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Effective Therapy Targeting Cytochrome bc1 Prevents Babesia Erythrocytic Development and Protects from Lethal Infection

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Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses: e1005324

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Mechanism of Action of ELQ-316 Against Toxoplasma gondii: Evidence for Qi Site Inhibition of Cytochrome bc1

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Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells

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Endochin-like quinolone-300 and ELQ-316 inhibit Babesia bovis, B. bigemina, B. caballi and Theileria equi

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Targeting mitochondria in cancer therapy could provide a basis for the selective anti-cancer activity

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