FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells th...
FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming
About this item
Full title
Author / Creator
Hansen, Ivo S. , Krabbendam, Lisette , Bernink, Jochem H. , Loayza-Puch, Fabricio , Hoepel, Willianne , van Burgsteden, Johan A. , Kuijper, Elsa C. , Buskens, Christianne J. , Bemelman, Willem A. , Zaat, Sebastiaan A. J. , Agami, Reuven , Vidarsson, Gestur , van den Brink, Gijs R. , de Jong, Esther C. , Wildenberg, Manon E. , Baeten, Dominique L. P. , Everts, Bart and den Dunnen, Jeroen
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
CD103
+
dendritic cells (DC) are crucial for regulation of intestinal tolerance in humans. However, upon infection of the lamina propria this tolerogenic response is converted to an inflammatory response. Here we show that immunoglobulin A (IgA) immune complexes (IgA-IC), which are present after bacterial infection of the lamina propria, are...
Alternative Titles
Full title
FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming
Authors, Artists and Contributors
Author / Creator
Krabbendam, Lisette
Bernink, Jochem H.
Loayza-Puch, Fabricio
Hoepel, Willianne
van Burgsteden, Johan A.
Kuijper, Elsa C.
Buskens, Christianne J.
Bemelman, Willem A.
Zaat, Sebastiaan A. J.
Agami, Reuven
Vidarsson, Gestur
van den Brink, Gijs R.
de Jong, Esther C.
Wildenberg, Manon E.
Baeten, Dominique L. P.
Everts, Bart
den Dunnen, Jeroen
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_292a58835f16458d974a1336ef0a74da
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_292a58835f16458d974a1336ef0a74da
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03318-5
