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69 results for Vidarsson,+Gestur

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ArticlesPeer ReviewedFull Text
Antibody glycosylation in COVID-19
Author / Creator:Pongracz, Tamas ; Vidarsson, Gestur ; Wuhrer, Manfred
Publisher:New York: Springer US
Journal title:Glycoconjugate journal, 2022-06, Vol.39 (3), p.335-344
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The Ligands for Human IgG and Their Effector Functions
Author / Creator:de Taeye, Steven W. ; Rispens, Theo ; Vidarsson, Gestur
Publisher:Switzerland: MDPI AG
Journal title:Antibodies (Basel), 2019-04, Vol.8 (2), p.30
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Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination
Author / Creator:Larsen, Mads Delbo ; Lopez-Perez, Mary ; Dickson, Emmanuel Kakra ; Ampomah, Paulina ; Tuikue Ndam, Nicaise ; Nouta, Jan ; Koeleman, Carolien A. M. ; Ederveen, Agnes L. Hipgrave ; Mordmüller, Benjamin ; Salanti, Ali ; Nielsen, Morten Agertoug ; Massougbodji, Achille ; van der Schoot, C. Ellen ; Ofori, Michael F. ; Wuhrer, Manfred ; Hviid, Lars ; Vidarsson, Gestur
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-10, Vol.12 (1), p.5838-5838, Article 5838
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Macrophages eliminate circulating tumor cells after monoclonal antibody therapy
Author / Creator:Gül, Nuray ; Babes, Liane ; Siegmund, Kerstin ; Korthouwer, Rianne ; Bögels, Marijn ; Braster, Rens ; Vidarsson, Gestur ; ten Hagen, Timo L.M. ; Kubes, Paul ; van Egmond, Marjolein
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2014-02, Vol.124 (2), p.812-823
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Acquisition of Fc-afucosylation of PfEMP1-specific IgG is age-dependent and associated with clinical protection against malaria
Author / Creator:Lopez-Perez, Mary ; Seidu, Zakaria ; Larsen, Mads Delbo ; Wang, Wenjun ; Nouta, Jan ; Wuhrer, Manfred ; Vidarsson, Gestur ; Ofori, Michael F. ; Hviid, Lars
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-01, Vol.16 (1), p.237-12, Article 237
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Human IgE does not bind to human FcRn
Author / Creator:Brinkhaus, Maximilian ; van der Kooi, Elvera J. ; Bentlage, Arthur E. H. ; Ooijevaar-de Heer, Pleuni ; Derksen, Ninotska I. L. ; Rispens, Theo ; Vidarsson, Gestur
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-01, Vol.12 (1), p.62-62, Article 62
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The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement
Author / Creator:Brinkhaus, Maximilian ; Pannecoucke, Erwin ; van der Kooi, Elvera J. ; Bentlage, Arthur E. H. ; Derksen, Ninotska I. L. ; Andries, Julie ; Balbino, Bianca ; Sips, Magdalena ; Ulrichts, Peter ; Verheesen, Peter ; de Haard, Hans ; Rispens, Theo ; Savvides, Savvas N. ; Vidarsson, Gestur
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-10, Vol.13 (1), p.6073-6073, Article 6073
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Augmented antibody-based anticancer therapeutics boost neutrophil cytotoxicity
Author / Creator:Heemskerk, Niels ; Gruijs, Mandy ; Temming, A. Robin ; Heineke, Marieke H. ; Gout, Dennis Y. ; Hellingman, Tessa ; Tuk, Cornelis W. ; Winter, Paula J. ; Lissenberg-Thunnissen, Suzanne ; Bentlage, Arthur E.H. ; de Donatis, Marco ; Bögels, Marijn ; Rösner, Thies ; Valerius, Thomas ; Bakema, Jantine E. ; Vidarsson, Gestur ; van Egmond, Marjolein
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-03, Vol.131 (6), p.1-16
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Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential
Author / Creator:Stapleton, Nigel M. ; Andersen, Jan Terje ; Stemerding, Annette M. ; Bjarnarson, Stefania P. ; Verheul, Ruurd C. ; Gerritsen, Jacoline ; Zhao, Yixian ; Kleijer, Marion ; Sandlie, Inger ; de Haas, Masja ; Jonsdottir, Ingileif ; van der Schoot, C. Ellen ; Vidarsson, Gestur
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2011-12, Vol.2 (1), p.599, Article 599
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Human DC-SIGN and CD23 do not interact with human IgG
Author / Creator:Temming, A. Robin ; Dekkers, Gillian ; van de Bovenkamp, Fleur S. ; Plomp, H. Rosina ; Bentlage, Arthur E. H. ; Szittner, Zoltán ; Derksen, Ninotska I. L. ; Wuhrer, Manfred ; Rispens, Theo ; Vidarsson, Gestur
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-07, Vol.9 (1), p.9995-9995, Article 9995
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A functional spleen contributes to afucosylated IgG in humans
Author / Creator:Wojcik, Iwona ; Schmidt, David E. ; de Neef, Lisa A. ; Rab, Minke A. E. ; Meek, Bob ; de Weerdt, Okke ; Wuhrer, Manfred ; van der Schoot, C. Ellen ; Zwaginga, Jaap J. ; de Haas, Masja ; Falck, David ; Vidarsson, Gestur
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-12, Vol.11 (1), p.24045-24045, Article 24045
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N-linked Fc glycosylation is not required for IgG-B-cell receptor function in a GC-derived B-cell line
Author / Creator:Kissel, Theresa ; Derksen, Veerle F. A. M. ; Bentlage, Arthur E. H. ; Koeleman, Carolien ; Hafkenscheid, Lise ; van der Woude, Diane ; Wuhrer, Manfred ; Vidarsson, Gestur ; Toes, René E. M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-01, Vol.15 (1), p.393-393, Article 393
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Sequence variants influencing the regulation of serum IgG subclass levels
Author / Creator:Olafsdottir, Thorunn A. ; Thorleifsson, Gudmar ; Lopez de Lapuente Portilla, Aitzkoa ; Jonsson, Stefan ; Stefansdottir, Lilja ; Niroula, Abhishek ; Jonasdottir, Aslaug ; Eggertsson, Hannes P. ; Halldorsson, Gisli H. ; Thorlacius, Gudny E. ; Arnthorsson, Asgeir O. ; Bjornsdottir, Unnur S. ; Asselbergs, Folkert W. ; Bentlage, Arthur E. H. ; Eyjolfsson, Gudmundur I. ; Gudmundsdottir, Steinunn ; Gunnarsdottir, Kristbjorg ; Halldorsson, Bjarni V. ; Holm, Hilma ; Ludviksson, Bjorn R. ; Melsted, Pall ; Norddahl, Gudmundur L. ; Olafsson, Isleifur ; Saevarsdottir, Saedis ; Sigurdardottir, Olof ; Sigurdsson, Asgeir ; Temming, Robin ; Önundarson, Pall T. ; Thorsteinsdottir, Unnur ; Vidarsson, Gestur ; Sulem, Patrick ; Gudbjartsson, Daniel F. ; Jonsdottir, Ingileif ; Nilsson, Björn ; Stefansson, Kari
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-09, Vol.15 (1), p.8054-13, Article 8054
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neonatal Fc receptor as therapeutic target in IgG-mediated autoimmune diseases
Author / Creator:Sesarman, Alina ; Vidarsson, Gestur ; Sitaru, Cassian
Publisher:Basel: Basel : SP Birkhäuser Verlag Basel
Journal title:Cellular and molecular life sciences : CMLS, 2010-08, Vol.67 (15), p.2533-2550
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FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming
Author / Creator:Hansen, Ivo S. ; Krabbendam, Lisette ; Bernink, Jochem H. ; Loayza-Puch, Fabricio ; Hoepel, Willianne ; van Burgsteden, Johan A. ; Kuijper, Elsa C. ; Buskens, Christianne J. ; Bemelman, Willem A. ; Zaat, Sebastiaan A. J. ; Agami, Reuven ; Vidarsson, Gestur ; van den Brink, Gijs R. ; de Jong, Esther C. ; Wildenberg, Manon E. ; Baeten, Dominique L. P. ; Everts, Bart ; den Dunnen, Jeroen
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-02, Vol.9 (1), p.863-13, Article 863
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Anti-D monoclonal antibodies from 23 human and rodent cell lines display diverse IgG Fc-glycosylation profiles that determine their clinical efficacy
Author / Creator:Kumpel, Belinda M. ; Saldova, Radka ; Koeleman, Carolien A. M. ; Abrahams, Jodie L. ; Ederveen, Agnes Hipgrave ; Armour, Kathryn L. ; Olovnikova, Natalia I. ; Vidarsson, Gestur ; Kapur, Rick ; Rudd, Pauline M. ; Wuhrer, Manfred
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-01, Vol.10 (1), p.1464-1464, Article 1464
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Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge
Author / Creator:Stapleton, Nigel M. ; Brinkhaus, Maximilian ; Armour, Kathryn L. ; Bentlage, Arthur E. H. ; de Taeye, Steven W. ; Temming, A. Robin ; Mok, Juk Yee ; Brasser, Giso ; Maas, Marielle ; van Esch, Wim J. E. ; Clark, Mike R. ; Williamson, Lorna M. ; van der Schoot, C. Ellen ; Vidarsson, Gestur
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-05, Vol.9 (1), p.7363-7363, Article 7363
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Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation
Author / Creator:Sonneveld, Myrthe E. ; de Haas, Masja ; Koeleman, Carolien ; de Haan, Noortje ; Zeerleder, Sacha S. ; Ligthart, Peter C. ; Wuhrer, Manfred ; van der Schoot, C. Ellen ; Vidarsson, Gestur
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-08, Vol.7 (1), p.8187-9, Article 8187
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Glycoengineering HIV-1 Env creates ‘supercharged’ and ‘hybrid’ glycans to increase neutralizing antibody potency, breadth and saturation
Author / Creator:Crooks, Ema T. ; Grimley, Samantha L. ; Cully, Michelle ; Osawa, Keiko ; Dekkers, Gillian ; Saunders, Kevin ; Rämisch, Sebastian ; Menis, Sergey ; Schief, William R. ; Doria-Rose, Nicole ; Haynes, Barton ; Murrell, Ben ; Cale, Evan Mitchel ; Pegu, Amarendra ; Mascola, John R. ; Vidarsson, Gestur ; Binley, James M.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2018-05, Vol.14 (5), p.e1007024-e1007024
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IgG-Fc glycosylation before and after rituximab treatment in immune thrombocytopenia
Author / Creator:Schmidt, David E. ; de Haan, Noortje ; Sonneveld, Myrthe E. ; Porcelijn, Leendert ; van der Schoot, C. Ellen ; de Haas, Masja ; Zwaginga, Jaap-Jan ; Wuhrer, Manfred ; Vidarsson, Gestur
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-02, Vol.10 (1), p.3051, Article 3051
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Antibody glycosylation in COVID-19

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The Ligands for Human IgG and Their Effector Functions

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Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination

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Macrophages eliminate circulating tumor cells after monoclonal antibody therapy

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Acquisition of Fc-afucosylation of PfEMP1-specific IgG is age-dependent and associated with clinical protection against malaria

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Human IgE does not bind to human FcRn

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The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement

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Augmented antibody-based anticancer therapeutics boost neutrophil cytotoxicity

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Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential

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Human DC-SIGN and CD23 do not interact with human IgG

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A functional spleen contributes to afucosylated IgG in humans

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N-linked Fc glycosylation is not required for IgG-B-cell receptor function in a GC-derived B-cell line

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Sequence variants influencing the regulation of serum IgG subclass levels

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neonatal Fc receptor as therapeutic target in IgG-mediated autoimmune diseases

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FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming

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Anti-D monoclonal antibodies from 23 human and rodent cell lines display diverse IgG Fc-glycosylation profiles that determine their clinical efficacy

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Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge

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Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation

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Glycoengineering HIV-1 Env creates ‘supercharged’ and ‘hybrid’ glycans to increase neutralizing antibody potency, breadth and saturation

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IgG-Fc glycosylation before and after rituximab treatment in immune thrombocytopenia

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