Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression
Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Fractional killing is the main cause of tumour resistance to chemotherapy. This phenomenon is observed even in genetically identical cancer cells in homogeneous microenvironments. To understand this variable resistance, here we investigate the individual responses to TRAIL in a clonal population of HeLa cells using live-cell microscopy and computat...
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Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression
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TN_cdi_doaj_primary_oai_doaj_org_article_29db1d8ce1734f508ff800f6141230b0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_29db1d8ce1734f508ff800f6141230b0
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-02787-4