Macrophage-derived IL-1β/NF-κB signaling mediates parenteral nutrition-associated cholestasis
Macrophage-derived IL-1β/NF-κB signaling mediates parenteral nutrition-associated cholestasis
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Author / Creator
El Kasmi, Karim C. , Vue, Padade M. , Anderson, Aimee L. , Devereaux, Michael W. , Ghosh, Swati , Balasubramaniyan, Natarajan , Fillon, Sophie A. , Dahrenmoeller, Carola , Allawzi, Ayed , Woods, Crystal , McKenna, Sarah , Wright, Clyde J. , Johnson, Linda , D’Alessandro, Angelo , Reisz, Julie A. , Nozik-Grayck, Eva , Suchy, Frederick J. and Sokol, Ronald J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
In infants intolerant of enteral feeding because of intestinal disease, parenteral nutrition may be associated with cholestasis, which can progress to end-stage liver disease. Here we show the function of hepatic macrophages and phytosterols in parenteral nutrition-associated cholestasis (PNAC) pathogenesis using a mouse model that recapitulates th...
Alternative Titles
Full title
Macrophage-derived IL-1β/NF-κB signaling mediates parenteral nutrition-associated cholestasis
Authors, Artists and Contributors
Author / Creator
Vue, Padade M.
Anderson, Aimee L.
Devereaux, Michael W.
Ghosh, Swati
Balasubramaniyan, Natarajan
Fillon, Sophie A.
Dahrenmoeller, Carola
Allawzi, Ayed
Woods, Crystal
McKenna, Sarah
Wright, Clyde J.
Johnson, Linda
D’Alessandro, Angelo
Reisz, Julie A.
Nozik-Grayck, Eva
Suchy, Frederick J.
Sokol, Ronald J.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2a266070415e43ab8b818dd620dfebf5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2a266070415e43ab8b818dd620dfebf5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03764-1