Crystal structures of U6 snRNA-specific terminal uridylyltransferase
Crystal structures of U6 snRNA-specific terminal uridylyltransferase
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The terminal uridylyltransferase, TUT1, builds or repairs the 3′-oligo-uridylylated tail of U6 snRNA. The 3′-oligo-uridylylated tail is the Lsm-binding site for U4/U6 di-snRNP formation and U6 snRNA recycling for pre-mRNA splicing. Here, we report crystallographic and biochemical analyses of human TUT1, which revealed the mechanisms for the specifi...
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Full title
Crystal structures of U6 snRNA-specific terminal uridylyltransferase
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TN_cdi_doaj_primary_oai_doaj_org_article_2a46149eda164db9ab1f82348eeccc5c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2a46149eda164db9ab1f82348eeccc5c
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15788
