Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landsca...
Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity
About this item
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Author / Creator
Cindy Yang, S. Y. , Lien, Scott C. , Wang, Ben X. , Clouthier, Derek L. , Hanna, Youstina , Cirlan, Iulia , Zhu, Kelsey , Bruce, Jeffrey P. , El Ghamrasni, Samah , Iafolla, Marco A. J. , Oliva, Marc , Hansen, Aaron R. , Spreafico, Anna , Bedard, Philippe L. , Lheureux, Stephanie , Razak, Albiruni , Speers, Vanessa , Berman, Hal K. , Aleshin, Alexey , Haibe-Kains, Benjamin , Brooks, David G. , McGaha, Tracy L. , Butler, Marcus O. , Bratman, Scott V. , Ohashi, Pamela S. , Siu, Lillian L. and Pugh, Trevor J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Serial circulating tumor DNA (ctDNA) monitoring is emerging as a non-invasive strategy to predict and monitor immune checkpoint blockade (ICB) therapeutic efficacy across cancer types. Yet, limited data exist to show the relationship between ctDNA dynamics and tumor genome and immune microenvironment in patients receiving ICB. Here, we present an i...
Alternative Titles
Full title
Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity
Authors, Artists and Contributors
Author / Creator
Lien, Scott C.
Wang, Ben X.
Clouthier, Derek L.
Hanna, Youstina
Cirlan, Iulia
Zhu, Kelsey
Bruce, Jeffrey P.
El Ghamrasni, Samah
Iafolla, Marco A. J.
Oliva, Marc
Hansen, Aaron R.
Spreafico, Anna
Bedard, Philippe L.
Lheureux, Stephanie
Razak, Albiruni
Speers, Vanessa
Berman, Hal K.
Aleshin, Alexey
Haibe-Kains, Benjamin
Brooks, David G.
McGaha, Tracy L.
Butler, Marcus O.
Bratman, Scott V.
Ohashi, Pamela S.
Siu, Lillian L.
Pugh, Trevor J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2a55653c8f4a4ed888f461e4bdb5696f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2a55653c8f4a4ed888f461e4bdb5696f
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25432-7
