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Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression...

Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2acddc161e984fb29a05d7f50cd5c46f

Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration

About this item

Full title

Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-01, Vol.12 (1), p.1655-1655, Article 1655

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

To control sprouting angiogenesis, endothelial Notch signaling suppresses tip cell formation, migration, and proliferation while promoting barrier formation. Each of these responses may be regulated by distinct Notch-regulated effectors. Notch activity is highly dynamic in sprouting endothelial cells, while constitutive Notch signaling drives homeo...

Alternative Titles

Full title

Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2acddc161e984fb29a05d7f50cd5c46f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2acddc161e984fb29a05d7f50cd5c46f

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-05666-1

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