A Phase II trial of alternating osimertinib and gefitinib therapy in advanced EGFR-T790M positive no...
A Phase II trial of alternating osimertinib and gefitinib therapy in advanced EGFR-T790M positive non-small cell lung cancer: OSCILLATE
About this item
Full title
Author / Creator
Tan, Lavinia , Brown, Chris , Mersiades, Antony , Lee, Chee Khoon , John, Thomas , Kao, Steven , Newnham, Genni , O’Byrne, Kenneth , Parakh, Sagun , Bray, Victoria , Jasas, Kevin , Yip, Sonia , Wong, Stephen Q. , Ftouni, Sarah , Guinto, Jerick , Chandrashekar, Sushma , Clarke, Stephen , Pavlakis, Nick , Stockler, Martin R. , Dawson, Sarah-Jane and Solomon, Benjamin J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
In this phase II, single arm trial (ACTRN12617000720314), we investigate if alternating osimertinib and gefitinib would delay the development of resistance to osimertinib in advanced, non-small cell lung cancer (NSCLC) with the epidermal growth factor receptor (
EGFR)
T790M mutation (
n
= 47) by modulating selective pressure on resista...
Alternative Titles
Full title
A Phase II trial of alternating osimertinib and gefitinib therapy in advanced EGFR-T790M positive non-small cell lung cancer: OSCILLATE
Authors, Artists and Contributors
Author / Creator
Brown, Chris
Mersiades, Antony
Lee, Chee Khoon
John, Thomas
Kao, Steven
Newnham, Genni
O’Byrne, Kenneth
Parakh, Sagun
Bray, Victoria
Jasas, Kevin
Yip, Sonia
Wong, Stephen Q.
Ftouni, Sarah
Guinto, Jerick
Chandrashekar, Sushma
Clarke, Stephen
Pavlakis, Nick
Stockler, Martin R.
Dawson, Sarah-Jane
Solomon, Benjamin J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2aee772d175142968edb2117d86331be
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2aee772d175142968edb2117d86331be
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-46008-1
