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ArticlesPeer ReviewedFull Text
Gefitinib
Publisher:Oxford University Press
Journal title:American journal of health-system pharmacy, 2015-08, Vol.72 (16), p.1340
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Gefitinib plus chemotherapy versus placebo plus chemotherapy in EGFR -mutation-positive non-small-cell lung cancer after progression on first-line gefitinib (IMPRESS): a phase 3 randomised trial
Author / Creator:Soria, Jean-Charles, Prof ; Wu, Yi-Long, Prof ; Nakagawa, Kazuhiko, Prof ; Kim, Sang-We, Prof ; Yang, Jin-Ji, MD ; Ahn, Myung-Ju, Prof ; Wang, Jie, MD ; Yang, James Chih-Hsin, Prof ; Lu, You, Prof ; Atagi, Shinji, MD ; Ponce, Santiago, MD ; Lee, Dae Ho, Prof ; Liu, Yunpeng, Prof ; Yoh, Kiyotaka, MD ; Zhou, Jian-Ying, Prof ; Shi, Xiaojin, MD ; Webster, Alan, MSc ; Jiang, Haiyi, MD ; Mok, Tony S K, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-08, Vol.16 (8), p.990-998
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Gefitinib Plus Chemotherapy vs Gefitinib Alone in Untreated EGFR-Mutant Non-Small Cell Lung Cancer in Patients With Brain Metastases: The GAP BRAIN Open-Label, Randomized, Multicenter, Phase 3 Study
Author / Creator:Hou, Xue ; Li, Meichen ; Wu, Guowu ; Feng, Weineng ; Su, Jin ; Jiang, Honghua ; Jiang, Guanming ; Chen, Jing ; Zhang, Baishen ; You, Zhixuan ; Liu, Qing ; Chen, Likun
Publisher:United States: American Medical Association
Journal title:JAMA network open, 2023-02, Vol.6 (2), p.e2255050-e2255050
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Gefitinib
Author / Creator:Rocheleau, Jackie ; Paradise, Lee
Journal title:The Gale Encyclopedia of Cancer : A Guide to Cancer and Its Treatments: Cr-Lo, 2021, p.921-923
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Gefitinib versus vinorelbine plus cisplatin as adjuvant treatment for stage II–IIIA (N1–N2) EGFR-mutant NSCLC (ADJUVANT/CTONG1104): a randomised, open-label, phase 3 study
Author / Creator:Zhong, Wen-Zhao, Prof ; Wang, Qun, Prof ; Mao, Wei-Min, Prof ; Xu, Song-Tao, Prof ; Wu, Lin, Prof ; Shen, Yi, Prof ; Liu, Yong-Yu, Prof ; Chen, Chun, Prof ; Cheng, Ying, Prof ; Xu, Lin, Prof ; Wang, Jun, Prof ; Fei, Ke, Prof ; Li, Xiao-Fei, Prof ; Li, Jian, Prof ; Huang, Cheng, Prof ; Liu, Zhi-Dong, Prof ; Xu, Shun, Prof ; Chen, Ke-Neng, Prof ; Xu, Shi-Dong, Prof ; Liu, Lun-Xu, Prof ; Yu, Ping, Prof ; Wang, Bu-Hai, Prof ; Ma, Hai-Tao, Prof ; Yan, Hong-Hong, MD ; Yang, Xue-Ning, Prof ; Zhou, Qing, Prof ; Wu, Yi-Long, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018, Vol.19 (1), p.139-148
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Novel regulation of miR‐34a‐5p and HOTAIR by the combination of berberine and gefitinib leading to inhibition of EMT in human lung cancer
Author / Creator:Zheng, Fang ; Li, Jing ; Ma, ChangJu ; Tang, XiaoJuan ; Tang, Qing ; Wu, JingJing ; Chai, XiaoSu ; Xie, Jianhui ; Yang, Xiao‐bo ; Hann, Swei Sunny
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2020-05, Vol.24 (10), p.5578-5592
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ArticlesPeer ReviewedFull Text
Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma
Author / Creator:Mok, Tony S ; Wu, Yi-Long ; Thongprasert, Sumitra ; Yang, Jin-Ji ; Yang, Chih-Hsin ; Chu, Da-Tong ; Saijo, Nagahiro ; Sunpaweravong, Patrapim ; Han, Baohui ; Margono, Benjamin ; Ichinose, Yukito ; Nishiwaki, Yutaka ; Ohe, Yuichiro ; Chewaskulyong, Busyamas ; Jiang, Haiyi ; Duffield, Emma L ; Watkins, Claire L ; Armour, Alison A ; Fukuoka, Masahiro
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2009-09, Vol.361 (10), p.947-957
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Gefitinib — a novel targeted approach to treating cancer
Author / Creator:Herbst, Roy S. ; Fukuoka, Masahiro ; Baselga, José
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2004-12, Vol.4 (12), p.956-965
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NF-κB–driven suppression of FOXO3a contributes to EGFR mutation-independent gefitinib resistance
Author / Creator:Chiu, Ching-Feng ; Chang, Yi-Wen ; Kuo, Kuang-Tai ; Shen, Yu-Shiuan ; Liu, Chien-Ying ; Yu, Yang-Hao ; Cheng, Ching-Chia ; Lee, Kang-Yun ; Chen, Feng-Chi ; Hsu, Min-Kung ; Kuo, Tsang-Chih ; Ma, Jui-Ti ; Su, Jen-Liang
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (18), p.E2526-E2535
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Restricting extracellular Ca2+ on gefitinib-resistant non-small cell lung cancer cells reverses altered epidermal growth factor-mediated Ca2+ response, which consequently enhances gefitinib sensitivit...
Author / Creator:Kim, Mi Seong ; Kim, So Hui ; Yang, Sei Hoon ; Kim, Min Seuk
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2020-08, Vol.15 (8), p.e0238155-e0238155
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ArticlesPeer ReviewedFull Text
M2 macrophages reduce the effect of gefitinib by activating AKT/mTOR in gefitinib‐resistant cell lines HCC827/GR
Author / Creator:Xiao, Fengqi ; Liu, Ni ; Ma, Xinchun ; Qin, Jing ; Liu, Yanguo ; Wang, Xiuwen
Publisher:Melbourne: John Wiley & Sons Australia, Ltd
Journal title:Thoracic cancer, 2020-11, Vol.11 (11), p.3289-3298
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Inhibition of DNA‑PK by gefitinib causes synergism between gefitinib and cisplatin in NSCLC
Author / Creator:Pan, Chi ; Duan, Huuie ; Wu, Yinan ; Zhu, Chunpeng ; Yi, Chenghao ; Duan, Yin ; Lu, Demin ; Guo, Cheng ; Wu, Deqi ; Wang, Yanyan ; Fu, Xianhua ; Xu, Jing ; Chen, Yiding ; Luo, Meng ; Tian, Wei ; Pan, Tao ; Xu, Wenhong ; Zhang, Suzhan ; Huang, Jianjin
Publisher:Athens: Spandidos Publications
Journal title:International journal of oncology, 2020-10, Vol.57 (4), p.939-955
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Dacomitinib versus gefitinib as first-line treatment for patients with EGFR-mutation-positive non-small-cell lung cancer (ARCHER 1050): a randomised, open-label, phase 3 trial
Author / Creator:Wu, Yi-Long ; Cheng, Ying ; Zhou, Xiangdong ; Lee, Ki Hyeong ; Nakagawa, Kazuhiko ; Niho, Seiji ; Tsuji, Fumito ; Linke, Rolf ; Rosell, Rafael ; Corral, Jesus ; Migliorino, Maria Rita ; Pluzanski, Adam ; Sbar, Eric I ; Wang, Tao ; White, Jane Liang ; Nadanaciva, Sashi ; Sandin, Rickard ; Mok, Tony S
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-11, Vol.18 (11), p.1454-1466
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Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR
Author / Creator:Maemondo, Makoto ; Inoue, Akira ; Kobayashi, Kunihiko ; Sugawara, Shunichi ; Oizumi, Satoshi ; Isobe, Hiroshi ; Gemma, Akihiko ; Harada, Masao ; Harada, Toshiyuki ; Yoshizawa, Hirohisa ; Kinoshita, Ichiro ; Fujita, Yuka ; Okinaga, Shoji ; Hirano, Haruto ; Yoshimori, Kozo ; Ogura, Takashi ; Ando, Masahiro ; Miyazawa, Hitoshi ; Tanaka, Tomoaki ; Saijo, Yasuo ; Hagiwara, Koichi ; Morita, Satoshi ; Nukiwa, Toshihiro
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2010-06, Vol.362 (25), p.2380-2388
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miR‐1‐3p and miR‐206 sensitizes HGF‐induced gefitinib‐resistant human lung cancer cells through inhibition of c‐Met signalling and EMT
Author / Creator:Jiao, Demin ; Chen, Jun ; Li, Yu ; Tang, Xiali ; Wang, Jian ; Xu, Wei ; Song, Jia ; Li, You ; Tao, Huimin ; Chen, Qingyong
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2018-07, Vol.22 (7), p.3526-3536
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Reference EntriesFull Text
gefitinib
Publisher:Oxford University Press
Journal title:Concise Medical Dictionary, 2020
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ArticlesPeer ReviewedFull Text
Gefitinib Combined with Cetuximab for the Treatment of Lung Adenocarcinoma Harboring the EGFR–Intergenic Region (SEC61G) Fusion and EGFR Amplification
Author / Creator:Zhang, Guoqing ; Xia, Peiyi ; Zhao, Shanshan ; Yuan, Lulu ; Wang, Xiaosu ; Li, Xiangnan ; Li, Jindong
Publisher:Hoboken, USA: John Wiley & Sons, Inc
Journal title:The oncologist (Dayton, Ohio), 2021-11, Vol.26 (11), p.e1898-e1902
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ArticlesFull Text
Tumor‑released lncRNA H19 promotes gefitinib resistance via packaging into exosomes in non‑small cell lung cancer
Author / Creator:Lei, Yi ; Guo, Wang ; Chen, Bowang ; Chen, Lu ; Gong, Jiaxin ; Li, Weimin
Publisher:Greece: Spandidos Publications UK Ltd
Journal title:Oncology reports, 2018-12, Vol.40 (6), p.3438-3446
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Treatment of Non–Small-Cell Lung Cancer with Erlotinib or Gefitinib
Author / Creator:Cataldo, Vince D ; Gibbons, Don L ; Pérez-Soler, Román ; Quintás-Cardama, Alfonso
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2011-03, Vol.364 (10), p.947-955
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The cytotoxicity of gefitinib on patient‑derived induced pluripotent stem cells reflects gefitinib‑induced liver injury in the clinical setting
Author / Creator:Fujisaka, Yasuhito ; Nakagawa, Takatoshi ; Tomoda, Kiichiro ; Watanabe, Marina ; Matsunaga, Ninso ; Tamura, Yosuke ; Ikeda, Soichiro ; Imagawa, Akihisa ; Asahi, Michio
Publisher:Athens: Spandidos Publications
Journal title:Oncology letters, 2023-12, Vol.26 (6), p.1, Article 520
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Gefitinib

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Gefitinib plus chemotherapy versus placebo plus chemotherapy in EGFR -mutation-positive non-small-cell lung cancer after progression on first-line gefitinib (IMPRESS): a phase 3 randomised trial

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Gefitinib Plus Chemotherapy vs Gefitinib Alone in Untreated EGFR-Mutant Non-Small Cell Lung Cancer in Patients With Brain Metastases: The GAP BRAIN Open-Label, Randomized, Multicenter, Phase 3 Study

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Gefitinib

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Gefitinib versus vinorelbine plus cisplatin as adjuvant treatment for stage II–IIIA (N1–N2) EGFR-mutant NSCLC (ADJUVANT/CTONG1104): a randomised, open-label, phase 3 study

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Novel regulation of miR‐34a‐5p and HOTAIR by the combination of berberine and gefitinib leading to inhibition of EMT in human lung cancer

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Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma

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Gefitinib — a novel targeted approach to treating cancer

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NF-κB–driven suppression of FOXO3a contributes to EGFR mutation-independent gefitinib resistance

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Restricting extracellular Ca2+ on gefitinib-resistant non-small cell lung cancer cells reverses altered epidermal growth factor-mediated Ca2+ response, which consequently enhances gefitinib sensitivit...

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M2 macrophages reduce the effect of gefitinib by activating AKT/mTOR in gefitinib‐resistant cell lines HCC827/GR

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Inhibition of DNA‑PK by gefitinib causes synergism between gefitinib and cisplatin in NSCLC

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Dacomitinib versus gefitinib as first-line treatment for patients with EGFR-mutation-positive non-small-cell lung cancer (ARCHER 1050): a randomised, open-label, phase 3 trial

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Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR

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miR‐1‐3p and miR‐206 sensitizes HGF‐induced gefitinib‐resistant human lung cancer cells through inhibition of c‐Met signalling and EMT

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gefitinib

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Gefitinib Combined with Cetuximab for the Treatment of Lung Adenocarcinoma Harboring the EGFR–Intergenic Region (SEC61G) Fusion and EGFR Amplification

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Tumor‑released lncRNA H19 promotes gefitinib resistance via packaging into exosomes in non‑small cell lung cancer

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Treatment of Non–Small-Cell Lung Cancer with Erlotinib or Gefitinib

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The cytotoxicity of gefitinib on patient‑derived induced pluripotent stem cells reflects gefitinib‑induced liver injury in the clinical setting

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